Which of the following scientists discovered the antibiotic properties of Penicillium?

Correct Answer: A

Rationale: The correct answer is A: Alexander Fleming. He discovered the antibiotic properties of Penicillium in 1928. Fleming observed that a mold called Penicillium notatum inhibited the growth of bacteria, leading to the discovery of penicillin. Louis Pasteur is known for his work on pasteurization and microbiology, not penicillin. Joseph Lister is known for pioneering antiseptic surgery techniques. Edward Jenner is known for developing the smallpox vaccine, not penicillin. Fleming's discovery revolutionized medicine by introducing the first antibiotic, penicillin, which has saved countless lives.

Correct Answer: A

Rationale: The correct answer is A: Wasserman test, IFT. The patient's symptoms of diffuse alopecia and Pinkus' sign are suggestive of secondary syphilis. The Wasserman test and Immunofluorescence Test (IFT) are used to detect antibodies against Treponema pallidum, the bacterium causing syphilis. This would confirm or rule out syphilis as the underlying cause of the patient's symptoms. Choice B (T.pallidum Immobilization Test) is similar to the Wasserman test but less commonly used. Choice C (Detection of the nasal mucous membrane for M.leprae) is irrelevant as leprosy does not present with the described symptoms. Choice D (Consultation of neuropathist) is premature without ruling out syphilis first. Thus, the Wasserman test, IFT should be the initial examination to investigate the likely cause of the patient's symptoms.

Correct Answer: B

Rationale: The correct answer is B: autoclaving. Autoclaving is a process that uses high pressure and steam to achieve temperatures above the boiling point of water, typically around 121-134°C. This high heat and pressure are effective in destroying spore forms of microorganisms, which are highly resistant structures that can withstand boiling temperatures. Autoclaving ensures the complete destruction of spores, making it an effective method for sterilization. Rationale: A: Pasteurization uses lower heat compared to autoclaving and is not sufficient to destroy spore forms. C: Freezing does not effectively destroy spore forms, as most microorganisms can survive freezing temperatures. D: Boiling, while effective for many microorganisms, may not be sufficient to destroy spore forms due to their high resistance, unlike autoclaving.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is a synthetic antiprotozoal drug commonly used for wound infection prevention. 2. It is highly effective against Helicobacter pylori, a bacterium that causes stomach ulcers. 3. Metronidazole works by disrupting DNA structure in bacteria, leading to their death. 4. Chingamin (Chloroquine) is an antimalarial drug, not effective against Helicobacter pylori. 5. Doxycycline hydrochloride is an antibiotic used for bacterial infections, not specifically for H. pylori. 6. Aciclovir is an antiviral drug used for herpes infections, not effective against H. pylori. Summary: Metronidazole is the correct answer as it is specifically effective against H. pylori and commonly used for wound infection prevention. Other choices are incorrect as they target different types of infections.

Correct Answer: C

Rationale: The correct answer is C because bacterial enzymes like amylase and protease catalyze biochemical reactions like digestion. Amylase breaks down carbohydrates, while protease breaks down proteins. This process is essential for bacterial metabolism and nutrient acquisition. Choice A (Break down toxins) is incorrect because bacterial enzymes are primarily involved in nutrient breakdown, not toxin degradation. Choice B (Facilitate movement) is incorrect as enzymes are not directly involved in bacterial movement. Choice D (Promote spore formation) is incorrect because enzymes like amylase and protease are not directly involved in spore formation.

Correct Answer: A

Rationale: The correct answer is A: Centers for Disease Control and Prevention. The CDC is a U.S. government agency responsible for protecting public health and safety. The correct answer is the only choice that accurately reflects the agency's purpose. Choice B (Children's Disease Center) is incorrect because the CDC's scope is not limited to children's health. Choice C (Central Disaster Control Center) is incorrect as the CDC primarily focuses on disease prevention. Choice D (Central Drug Evaluation and Control Center) is incorrect as the CDC's main focus is not on drug evaluation. Thus, the correct answer is A as it aligns with the CDC's mission and responsibilities.

Correct Answer: D

Rationale: The correct answer is D because all three choices, Clostridium botulinum, Morbillivirus morbillorum, and Clostridium tetani, can cause infections of the central nervous system (CNS). Clostridium botulinum can lead to botulism, which affects the nervous system. Morbillivirus morbillorum can cause measles, which can lead to viral encephalitis. Clostridium tetani can cause tetanus, which affects the CNS by producing neurotoxins. Therefore, all three choices are pathogens that can cause infections of the CNS.

Correct Answer: A

Rationale: The correct answer is A: The lysozyme hydrolyzes the glycoside bonds between the N-acetylmuramic acid and the N-acetylglucosamine in the peptidoglycan of the cell wall. This is because lysozyme is an enzyme that specifically targets the peptidoglycan layer of bacterial cell walls, breaking down the structure by cleaving the glycosidic bonds between these two specific sugar molecules. This action weakens the cell wall, leading to bacterial cell lysis. The other choices are incorrect because lysozyme does not target phosphate bonds in phospholipids (B), disulfide bonds in immunoglobulins (C), or hydrogen bonds in bacterial capsules (D).

Correct Answer: A

Rationale: The correct answer is A: Bacteriological. This method involves isolating and culturing the causative bacteria from the wound material to determine the species. This allows for further testing to confirm gaseous gangrene and identify the specific pathogen. Choice B: Allergic is incorrect as it pertains to immune responses, not identifying bacteria. Choice C: Bacterioscopic is incorrect as it refers to microscopic examination of bacteria, not species identification. Choice D: Serological is incorrect as it involves testing for antibodies in the blood, not identifying the causative agent directly.