ATI RN
foundations in microbiology test bank Questions
Question 1 of 9
Which of the following organisms produces aflatoxin, a carcinogenic substance?
Correct Answer: C
Rationale: Step-by-step rationale: 1. Aspergillus flavus is a fungus known to produce aflatoxin. 2. Aflatoxin is a potent carcinogen found in contaminated food. 3. Candida albicans is a yeast species not associated with aflatoxin production. 4. Claviceps purpurea is a fungus that produces ergot alkaloids, not aflatoxin. 5. Staphylococcus aureus is a bacterium known for causing food poisoning, not aflatoxin production. Summary: Aspergillus flavus is the correct answer as it is the organism known to produce aflatoxin, a carcinogenic substance. Other choices are incorrect as they are not associated with aflatoxin production.
Question 2 of 9
All statements about plasmids are correct except:
Correct Answer: C
Rationale: The correct answer is C because plasmids do not encode essential bacterial properties. They are non-essential, extra-chromosomal DNA molecules that can replicate independently within bacterial cells. Plasmids mainly contain genes for antibiotic resistance, genetic transfer, and other specific functions. Choice A is correct as many plasmids do carry antibiotic resistance genes. Choice B is also accurate as plasmids are indeed smaller, circular, and exist outside the bacterial chromosome. Choice D is true as plasmids can facilitate bacterial conjugation, allowing the transfer of genetic material between bacteria.
Question 3 of 9
Microscopic examination of a smear from a chancre revealed spiral microorganisms. The bacteria were thin and mobile with 8-12 regular coils. What is the likely diagnosis?
Correct Answer: A
Rationale: The correct diagnosis is A: Syphilis. The spiral microorganisms described are characteristic of Treponema pallidum, the causative agent of syphilis. The thin and mobile bacteria with 8-12 regular coils match the morphology of Treponema pallidum. Leptospirosis is caused by Leptospira interrogans, which are thicker and have hook-like ends, different from the described bacteria. Lyme disease is caused by Borrelia burgdorferi, which has a different appearance than the thin, coiled bacteria in the smear. Relapsing fever is caused by Borrelia recurrentis, which typically have irregular coils, unlike the regular coils seen in the smear.
Question 4 of 9
Which of the following diseases is considered to fall in the group II category?
Correct Answer: C
Rationale: The correct answer is C: Mumps. Group II diseases are vaccine-preventable diseases that are communicable and can cause outbreaks. Mumps fits this criteria as it is preventable through vaccination, easily transmitted through respiratory droplets, and can lead to outbreaks in communities. Anthrax (A) is a zoonotic disease, Lyme disease (B) is transmitted by ticks, and Smallpox (D) has been eradicated.
Question 5 of 9
Which statement for immunomodulators is correct
Correct Answer: C
Rationale: Rationale: Choice C is correct because immunomodulators can indeed be natural (e.g., cytokines) or artificial compounds (e.g., synthetic peptides). They work by modulating the immune response, enhancing or suppressing it as needed. Choice A is incorrect because immunomodulators can stimulate both humoral and cellular immune responses. Choice B is incorrect as isoniazid is primarily an antibiotic used to treat tuberculosis, not an immunomodulator. Choice D is incorrect because immunomodulators can have varying effects on the immune response, not just suppress it.
Question 6 of 9
After 4 months of treatment for tuberculosis the patient began complaining of toes and fingers numbness, sensation of creeps. He was diagnosed with polyneuritis. What antituberculous drug might have caused these complications?
Correct Answer: A
Rationale: The correct answer is A: Isoniazid. Isoniazid is known to cause peripheral neuropathy as a side effect, especially with prolonged use. It can lead to symptoms such as numbness, tingling, and weakness in the toes and fingers due to its neurotoxic effects. Rifampicin (B) is less likely to cause neuropathy. Ciprofloxacin (C) is not typically associated with neuropathy. Sodium salt of benzylpenicillin (D) is an antibiotic but is not known to cause polyneuritis.
Question 7 of 9
Which bacteria is commonly associated with foodborne illnesses?
Correct Answer: B
Rationale: The correct answer is B: Campylobacter jejuni. This bacteria is commonly associated with foodborne illnesses due to its presence in undercooked poultry and unpasteurized milk. Campylobacteriosis is a leading cause of bacterial gastroenteritis. Streptococcus pneumoniae (A) causes pneumonia, not foodborne illnesses. Mycobacterium tuberculosis (C) causes tuberculosis, not foodborne illnesses. Haemophilus influenzae (D) can cause respiratory infections but is not commonly associated with foodborne illnesses.
Question 8 of 9
Which one is not true for the adaptive immunity:
Correct Answer: A
Rationale: The correct answer is A because adaptive immunity is not mainly observed in the skin and mucous membranes. Adaptive immunity is a systemic response that involves specific immune cells and antibodies targeting specific pathogens. It develops immune memory (B), meaning it can recognize and respond faster upon re-exposure to the same pathogen. Adaptive immunity also has specificity (C), as it can target specific antigens. Lastly, adaptive immunity is not evolutionarily newer in comparison to innate immunity (D), as both systems have co-evolved to provide comprehensive protection against pathogens.
Question 9 of 9
The mold responsible for the production of penicillin belongs to the subgroup of:
Correct Answer: B
Rationale: The correct answer is B: Ascomycota. Penicillin is produced by the mold Penicillium, which belongs to the phylum Ascomycota. Ascomycota is known for its sac-like structures called asci that contain ascospores. Penicillium produces penicillin as a defense mechanism against bacteria. Basidiomycota (A) are known for producing mushrooms, Zygomycota (C) includes bread molds like Rhizopus, and Deuteromycota (D) is a classification for fungi with no known sexual reproductive stage.