Which of the following organisms belongs in the group I category?

Correct Answer: C

Rationale: The correct answer is C: Helicobacter pylori. Group I organisms are classified based on their low infectious doses and potential for bioterrorism. H. pylori is known to cause gastric ulcers and is categorized as a Group I organism due to its ability to cause disease at low doses. A: Francisella tularensis is a Group A bioterrorism agent, not Group I. B: Clostridium difficile is not typically classified as a Group I organism. D: Bacillus anthracis is a Group A bioterrorism agent, not Group I.

Correct Answer: D

Rationale: The correct answer is D because the rubella virus has icosahedral symmetry, meaning it has a spherical shape with 20 equilateral triangular faces. This symmetry is common in many viruses and allows for efficient packaging of genetic material. Choice A is incorrect because the rubella virus does have glycoprotein spikes on its surface. These spikes help the virus attach to host cells. Choice B is incorrect because the rubella virus does have an envelope derived from the host cell membrane. This envelope plays a role in viral entry into host cells. Choice C is incorrect because the rubella virus is an ssRNA virus, not ssDNA. Its genetic material is single-stranded RNA, not DNA. In summary, the rubella virus has icosahedral symmetry and possesses glycoprotein spikes, an envelope, and ssRNA genetic material, making choices A, B, and C incorrect.

Correct Answer: C

Rationale: The correct answer is C: Thermophiles. Thermophiles are bacteria that thrive in high temperatures typically above 45°C. They have specialized enzymes and cellular structures that allow them to survive and even thrive in extreme heat. Psychrophiles (A) are adapted to cold temperatures, mesophiles (B) thrive at moderate temperatures, and halophiles (D) prefer high salt concentrations, making them unsuitable for extreme heat survival. Therefore, Thermophiles are the only bacteria among the choices that are known for their ability to survive in extreme heat.

Correct Answer: A

Rationale: The correct answer is A: Helicobacter pylori. Rationale: 1. Gram-negative spiral-shaped microorganisms match the morphology of Helicobacter pylori. 2. Positive urease activity is a characteristic feature of Helicjsonacter pylori. 3. Helicobacter pylori is specifically associated with gastric ulcers and is a common pathogen in the gastrointestinal tract. Summary: Choice B, Campilobacter jejuni, is a gram-negative curved bacterium but is not typically associated with gastric ulcers or urease activity. Choice C, Treponema pallidum, is a spirochete bacterium causing syphilis, which is not related to gastric ulcers. Choice D, Spirilla minor, is a generic term for spiral-shaped bacteria and is not a specific pathogen associated with gastric ulcers or urease activity.

Correct Answer: C

Rationale: The correct answer is C: Gram-negative bacterial outer membrane. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria. LPS consist of lipid A, core oligosaccharide, and O-antigen. They play a crucial role in the structural integrity and protection of Gram-negative bacteria. Choice A (Gram-positive bacteria) is incorrect because LPS are not present in Gram-positive bacteria. Choice B (Fungal cell walls) is incorrect as LPS are specific to bacterial outer membranes. Choice D (Viral capsids) is incorrect as LPS are not associated with viral structures.

Correct Answer: D

Rationale: Interferon is a cell-specific protein that is produced and released from infected cells in response to viral infections. It acts extracellularly to interfere with viral replication, not to inactivate the virus itself. Interferon is not coded for by cellular DNA, but by viral RNA during infection. Therefore, the correct answer, D, is that interferon is not virus-specific but is cell-specific. This is because interferon can be produced by various cell types in response to different types of viral infections, making it a broad-spectrum antiviral defense mechanism.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Tularemia is caused by Francisella tularensis, a highly infectious bacterium. 2. Francisella tularensis is the only pathogen specifically known to cause tularemia. 3. The other choices (Bordetella pertussis, Brucella suis, Legionella sp.) are not associated with tularemia. 4. Therefore, the correct answer is A - Francisella tularensis.

Correct Answer: B

Rationale: The correct answer is B: Ethambutol. Ethambutol is known to cause optic neuritis, affecting the visual nerve. It is a well-documented side effect of this drug. Isoniazid (Choice A) is associated with peripheral neuropathy, not optic neuritis. Kanamycin (Choice C) is known for its side effects on the inner ear, causing hearing loss. Rifampicin (Choice D) is not typically associated with optic neuritis but can cause other adverse effects like hepatitis. By process of elimination and knowledge of drug side effects, Ethambutol is the most likely culprit.

Correct Answer: B

Rationale: The correct answer is B: lyophilization. This technique involves freezing the sample and then removing the ice through sublimation, preserving the cells in a dry state. Desiccation (A) simply involves drying without freezing. Pasteurization (C) is a heat treatment to kill pathogens, not used for preservation. Radiation (D) can sterilize but doesn't involve freezing and drying like lyophilization.