Which of the following opioids would be contraindicated in this patient?

Correct Answer: A

Rationale: In a patient with acute myocardial infarction, morphine would be contraindicated due to its potential to cause hypotension and respiratory depression, which can exacerbate the patient's condition.

Correct Answer: A

Rationale: Amitriptyline is a tricyclic antidepressant that increases the availability of norepinephrine and serotonin, making it a likely choice for the treatment of depression in this patient.

Correct Answer: A

Rationale: GABA receptor blockers typically have proconvulsant activity rather than anticonvulsant effects.

Correct Answer: D

Rationale: The recently approved drug that acts with a novel mechanism of action, a noncompetitive blockade of AMPA receptors on brain neurons, is Perampanel. Given that the patient had poorly controlled seizures with valproic acid, adding Perampanel would provide a different mechanism of action to improve seizure control.

Correct Answer: A

Rationale: Epinephrine is poorly absorbed through unbroken skin but is effective on mucosal surfaces.