ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 9
Which of the following opioid analgesics has very low protein binding?
Correct Answer: A
Rationale: Morphine has very low protein binding compared to other opioids allowing it to have more free drug available in circulation.
Question 2 of 9
Epinephrine HCl has little or no effect on
Correct Answer: A
Rationale: Epinephrine is poorly absorbed through unbroken skin but is effective on mucosal surfaces.
Question 3 of 9
Cervical priming with prostaglandin results in
Correct Answer: C
Rationale: Prostaglandins soften and dilate the cervix, facilitating labor induction.
Question 4 of 9
Buspirone is:
Correct Answer: D
Rationale: Buspirone (choice D), a 5-HT1A partial agonist, treats anxiety without sedation (choice A), isn't for insomnia (choice B), and has a slow onset (choice C incorrect), taking weeks. Its anxiolytic action offers a non-addictive alternative to benzodiazepines.
Question 5 of 9
A first-year surgery intern has rotated on numerous surgical services. He has gotten quite used to ordering morphine for pain control. However, which of the following is an absolute contraindication to opioid use?
Correct Answer: A
Rationale: Closed head injury (choice A) contraindicates morphine due to respiratory depression and ICP elevation, masking neurological signs. MI (choice B), pulmonary edema (choice C), and diarrhea (choice D) benefit from morphine. This exception ensures safety.
Question 6 of 9
A 14-year-old girl is brought to the emergency room as her mother observed that her daughter experienced frequent impairments of consciousness lasting for about 30 seconds. Neurological evaluation indicates 'Absence seizures'. With which of the following drugs should we start treatment?
Correct Answer: C
Rationale: Ethosuximide (choice C) treats absence seizures by reducing T-type calcium currents, ideal for brief consciousness lapses. Alprazolam (choice A), Diazepam (choice B), and Midazolam (choice D), benzodiazepines, aren't first-line for absence. Ethosuximide's specificity is key.
Question 7 of 9
Compared with other antidepressant drugs, mirtazapine has the distinctive ability to act as an antagonist of
Correct Answer: A
Rationale: Mirtazapine enhances norepinephrine and serotonin release by blocking presynaptic alpha2 receptors.
Question 8 of 9
Following is an amide-linked local anesthetic
Correct Answer: A
Rationale: Bupivacaine is an amide local anesthetic; procaine and tetracaine are esters.
Question 9 of 9
Match the description with the appropriate agent.
Correct Answer: A
Rationale: Cimetidine decreases theophylline clearance; Ipratropium has anticholinergic activity with few side effects; Albuterol has high β2-adrenergic selectivity.