Which of the following new drug is indicated in managing SIADH, non – peptide and competitive antagonist of ADH’s water sparing effects in the collecting ducts of nephron?

Correct Answer: D

Rationale: The correct answer is D: Conivaptan. Conivaptan is a non-peptide competitive antagonist of ADH, indicated for managing SIADH by blocking ADH's water-sparing effects in the collecting ducts. Mannitol (A) is an osmotic diuretic used for reducing intracranial pressure, not specifically for SIADH. Bumetanide (B) is a loop diuretic used for conditions like heart failure and edema. Spironolactone (C) is a potassium-sparing diuretic used for conditions like hypertension and heart failure, not specifically for SIADH.

Correct Answer: C

Rationale: The correct answer is C: Encourage fluid intake of 3000 mL/day. This is important post-nephrolithotomy to prevent urinary stasis and aid in flushing out potential stone fragments. Adequate hydration also helps in preventing urinary tract infections. Administering IV fluids and blood transfusions (A) may be necessary in certain cases, but not specifically indicated for this scenario. Administering narcotic analgesics (B) may be required for pain management, but it does not address the underlying issue of preventing complications. Suggesting herbs or spices (D) is unrelated and may not be recommended due to potential interactions with medications.

Correct Answer: C

Rationale: The correct answer is C because hematuria (blood in urine) and change in urinary pattern are classic symptoms of bladder cancer. Hematuria is the most common presenting symptom. Weight loss and low back pain (choice A) are more indicative of advanced stages of cancer. Fatigue and anemia (choice B) are nonspecific symptoms. Difficulty initiating urinary stream and nocturia (choice D) may be seen in other conditions but are not specific to bladder cancer.

Correct Answer: D

Rationale: The correct answer is D because soaking in a tub with bubble bath can exacerbate cystitis symptoms due to potential irritation from the bubble bath chemicals. This can worsen the patient's condition. A, B, and C are correct statements. A promotes proper hydration, B encourages regular emptying of the bladder to prevent bacterial growth, and C suggests a potential remedy for cystitis by consuming cranberry juice.

Correct Answer: A

Rationale: The correct answer is A: Yes. The question asks for a preference, and "Yes" indicates a positive desire to go to the park. Choosing "No" (B) indicates a lack of interest. "Maybe" (C) suggests uncertainty, and "I don't know" (D) shows indecision. Therefore, selecting "Yes" aligns with the question and expresses a clear preference, making it the correct answer.