ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
Which of the following MHC class II genes has the most alleles (most polymorphic)?
Correct Answer: D
Rationale: DRβ is the most polymorphic among MHC class II genes.
Question 2 of 5
Which of the following is NOT true of T-cell receptors, when compared to immunoglobulin?
Correct Answer: D
Rationale: TCRs do not undergo somatic hypermutation or class switching, unlike immunoglobulins.
Question 3 of 5
A protein of herpes simplex virus (HSV) binds to TAP and inhibits peptide transport into the endoplasmic reticulum. What is a consequence of this?
Correct Answer: A
Rationale: Inhibiting TAP prevents peptides from reaching the ER, reducing their expression on the cell surface via MHC Class I.
Question 4 of 5
Leukocyte-specific protein tyrosine kinase (Lck) is integral in the signaling cascade in cells. Zeta-chain-associated protein kinase 70 (ZAP-70), which binds CD3-zeta, is cell specific. Spleen tyrosine kinase (Syk), a signal transmitter, is found predominantly in cells.
Correct Answer: D
Rationale: Lck and ZAP-70 are T cell-specific (TCR signaling), while Syk is predominant in B cells (BCR signaling).
Question 5 of 5
Combat certain parasitic infections (e.g. worms); hydrolytic enzymes
Correct Answer: C
Rationale: Eosinophils target parasites with hydrolytic enzymes.