ATI RN
microbiology basic and clinical principles test bank Questions
Question 1 of 9
Which of the following methods can be used for diagnosis of respiratory tract infections
Correct Answer: D
Rationale: The correct answer is D: All are correct. Culture of samples from the respiratory tract can identify specific pathogens, Immunofluorescence can detect viral antigens, and PCR can amplify and detect specific DNA/RNA sequences. Using all methods together provides a comprehensive approach for diagnosing respiratory tract infections. Culture alone may miss fastidious organisms, Immunofluorescence has limitations in sensitivity, and PCR requires specific primers. Therefore, combining these methods increases the likelihood of accurate diagnosis by covering a range of pathogens and improving sensitivity and specificity.
Question 2 of 9
Unlike eukaryotic cytoplasm, the prokaryotic one is:
Correct Answer: B
Rationale: The correct answer is B: Simpler. Prokaryotic cytoplasm is simpler than eukaryotic cytoplasm because prokaryotic cells lack membrane-bound organelles such as a nucleus, mitochondria, and endoplasmic reticulum that are present in eukaryotic cells. Prokaryotic cytoplasm contains fewer components and structures compared to eukaryotic cytoplasm, making it less complex. Therefore, the prokaryotic cytoplasm is simpler in structure. Choices A, C, and D are incorrect because prokaryotic cytoplasm is not more complex than eukaryotic cytoplasm, there is a clear difference in structure between prokaryotic and eukaryotic cytoplasm, and the statement "None of the above" is not accurate as the correct answer is B.
Question 3 of 9
The Wasserman reaction is markedly positive (++++) in a 30-year-old man. What infectious disease is diagnosed using the Wasserman reaction?
Correct Answer: B
Rationale: The correct answer is B: Syphilis. The Wasserman reaction is a test for syphilis, specifically for detecting antibodies against the bacterium Treponema pallidum. In a 30-year-old man with a markedly positive Wasserman reaction, it indicates an active syphilis infection. Brucellosis (Choice A) is not diagnosed using the Wasserman reaction. Poliomyelitis (Choice C) is a viral infection affecting the spinal cord, not diagnosed using the Wasserman reaction. Influenza (Choice D) is a respiratory viral infection, not associated with the Wasserman reaction.
Question 4 of 9
The infectious (non-sterile) immunity is:
Correct Answer: C
Rationale: The correct answer is C because infectious (non-sterile) immunity is achieved through the persistence of the infectious agent in the body, allowing the immune system to continuously recognize and combat the pathogen. This type of immunity provides long-lasting protection against future infections by the same agent. Choice A (cross-reactivity of antibodies) is incorrect as it refers to the ability of antibodies to recognize similar antigens, not necessarily related to infectious immunity. Choice B (toxemia and formation of antitoxic antibodies) is incorrect as it specifically relates to toxins produced by pathogens and the corresponding antibody response, not the persistence of the infectious agent itself. Choice D (neutralization of infectious agent) is incorrect as it describes the process of antibodies binding to and inactivating pathogens, but it does not necessarily lead to long-term immunity through the persistence of the infectious agent.
Question 5 of 9
A blood culture from a patient with sepsis revealed Gram-negative diplococci. The bacteria were oxidase-positive and fermentative. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Neisseria meningitidis. Step 1: Gram-negative diplococci - characteristic of Neisseria species. Step 2: Oxidase-positive - Neisseria species are oxidase-positive. Step 3: Fermentative - Neisseria meningitidis is a fermentative bacterium. Therefore, Neisseria meningitidis is the most likely causative agent. Summary: - B: Neisseria gonorrhoeae is also a Neisseria species but is not fermentative. - C: Moraxella catarrhalis is oxidase-positive but not fermentative. - D: Haemophilus influenzae is not a Neisseria species and is not typically fermentative.
Question 6 of 9
Name the halogen-containing antiseptic with fungicidal properties, which is used to treat dermatomycosis:
Correct Answer: A
Rationale: Rationale: 1. Iodine solution contains iodine, a halogen with antiseptic properties. 2. Iodine is effective against fungi, making it suitable for treating dermatomycosis. 3. Iodine solution is commonly used in dermatology for its fungicidal properties. 4. Formalin, methylene blue, and brilliant green do not contain halogens or have fungicidal properties. Summary: - Formalin is a disinfectant, not an antiseptic for dermatomycosis. - Methylene blue is an antifungal dye, not used as an antiseptic. - Brilliant green is an antiseptic, but does not contain halogens or have fungicidal properties.
Question 7 of 9
What reaction is catalyzed by a beta-lactamase enzyme
Correct Answer: C
Rationale: The correct answer is C: the hydrolysis of the four-membered ring present in penicillin. Beta-lactamase enzyme catalyzes the hydrolysis of the four-membered beta-lactam ring present in penicillin, rendering the antibiotic ineffective against bacterial cell walls. This enzyme breaks the bond in the beta-lactam ring, thus inactivating the antibiotic. Incorrect choices: A: the final cross-linking reaction to form the bacterial cell wall - This is incorrect as beta-lactamase does not participate in the formation of bacterial cell walls. B: the biosynthesis of the penicillin structure from the amino acid valine and cysteine - This is incorrect as beta-lactamase is not involved in the biosynthesis of penicillin. D: the hydrolysis of the acyl side chain from penicillin structures - This is incorrect as beta-lactamase specifically targets the beta-lactam ring, not the
Question 8 of 9
The virulence factors of bacteria include:
Correct Answer: B
Rationale: Rationale: The correct answer is B because virulence factors of bacteria are characteristics that enable them to cause disease. Colonization allows bacteria to establish and multiply in the host. Invasion refers to the ability to penetrate host tissues. Toxins are substances produced by bacteria that harm the host. Adhesion is crucial for bacteria to attach to host cells. A: Size and mutation are not typical virulence factors. Resistance is not directly related to causing disease. C: While toxins and evasion of body defenses are correct, motility and size are not universally considered virulence factors. D: Chemotaxis and fermentation are not primary virulence factors, unlike colonization and toxins.
Question 9 of 9
The organism that is responsible for the vast majority of cases of fungal vaginitis is:
Correct Answer: D
Rationale: The correct answer is D: Propionibacterium acnes. This bacterium is not a fungus, but a common skin bacteria. Fungal vaginitis is typically caused by Candida albicans or other fungal species, not by bacteria like Escherichia coli, Streptococcus agalactiae, or Klebsiella oxytoca. Propionibacterium acnes is not associated with vaginal infections, making it the correct answer in this context.