ATI RN
Advanced Pharmacology Across the Lifespan Questions
Question 1 of 5
Which of the following medications is used to treat schizophrenia by blocking dopamine receptors?
Correct Answer: A
Rationale: The correct answer is A: Olanzapine. Olanzapine is an atypical antipsychotic that works by blocking dopamine receptors in the brain, reducing dopamine activity and alleviating symptoms of schizophrenia. Citalopram and Fluoxetine are both selective serotonin reuptake inhibitors used to treat depression and anxiety, not schizophrenia. Lorazepam is a benzodiazepine used for anxiety disorders, not schizophrenia. Blocking dopamine receptors is key in managing schizophrenia symptoms, making olanzapine the appropriate choice.
Question 2 of 5
A patient with a history of chronic pain is prescribed tramadol. Tramadol works primarily by:
Correct Answer: B
Rationale: The correct answer is B: Inhibiting the reuptake of serotonin and norepinephrine. Tramadol is a centrally-acting synthetic opioid analgesic that works by inhibiting the reuptake of these neurotransmitters in the brain. This action enhances their analgesic effects, providing pain relief. Choice A is incorrect because tramadol's mechanism is not primarily through binding to opioid receptors like traditional opioids. Choice C is incorrect as tramadol does not directly inhibit prostaglandin synthesis. Choice D is incorrect as tramadol does not primarily block sodium channels in peripheral nerves.
Question 3 of 5
A patient with chronic pain is prescribed tramadol. Tramadol works primarily by:
Correct Answer: B
Rationale: The correct answer is B because tramadol primarily works by inhibiting the reuptake of serotonin and norepinephrine. This mechanism of action helps to modulate the perception of pain in the central nervous system. Tramadol's opioid activity is weaker compared to other opioids, so it is not the primary mechanism of action. Inhibiting prostaglandin synthesis is the mechanism of NSAIDs, not tramadol. Blocking sodium channels in peripheral nerves is the mechanism of local anesthetics, not tramadol. Therefore, choice B is the most appropriate mechanism of action for tramadol in managing chronic pain.
Question 4 of 5
Which of the following drugs is used to treat infection with Plasmodium (malaria)?
Correct Answer: C
Rationale: Rationale: Chloroquine is the correct answer as it is a well-established antimalarial drug targeting Plasmodium. It works by inhibiting the parasite's ability to break down hemoglobin. Clindamycin (A), Doxycycline (B), and Penicillin (D) are not typically used for treating malaria. Clindamycin is more commonly used for anaerobic infections, Doxycycline for bacterial infections, and Penicillin for bacterial infections unrelated to malaria.
Question 5 of 5
Which of the following medications is used to treat osteoporosis by increasing bone mineral density?
Correct Answer: A
Rationale: Step-by-step rationale for choice A: Alendronate: 1. Alendronate is a bisphosphonate medication that works by inhibiting bone resorption, leading to increased bone mineral density. 2. It is commonly prescribed for the treatment of osteoporosis to reduce the risk of fractures. 3. By increasing bone density, alendronate helps strengthen bones and prevent further bone loss in osteoporosis patients. Summary: - Choice B: Ranitidine is used to reduce stomach acid production and treat ulcers, not osteoporosis. - Choice C: Ibuprofen is a nonsteroidal anti-inflammatory drug used for pain relief, not for increasing bone density. - Choice D: Propranolol is a beta-blocker used to treat high blood pressure and certain heart conditions, not osteoporosis.