ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
Which of the following is used to enumerate and/or separate live cells that express an antigen, sorted by applying an electric charge to the stained cells?
Correct Answer: C
Rationale: FACS (fluorescence-activated cell sorting) uses fluorescence and electric charge to sort live cells based on antigen expression, unlike the other methods which do not involve cell sorting.
Question 2 of 5
Production of secreted antibodies (pAs site) involves a chain of amino acids with a stretch of charged (versus non charged) amino acids at the terminus, in comparison to membrane bound antibody production (pAm site).
Correct Answer: B
Rationale: Secreted antibodies have a shorter, charged COOH terminus compared to the longer, hydrophobic terminus of membrane-bound antibodies.
Question 3 of 5
Which of the following TCR genetic chains contains V and J segments, similar to genes for immunoglobulin kappa and lambda light chains?
Correct Answer: D
Rationale: Gamma (γ) and alpha (α) chains contain V and J segments, analogous to light chain genes.
Question 4 of 5
Which of the following molecules is necessary (not accessory) for antigen recognition and T cell activation?
Correct Answer: B
Rationale: CD3 is essential for TCR signaling and T cell activation, unlike the accessory roles of CD4 and CD8.
Question 5 of 5
MHC class I has three genes (HLA-A, HLA-B, & HLA-C). Which of the following is the correct order from most alleles (most polymorphic) to least alleles?
Correct Answer: C
Rationale: HLA-B is the most polymorphic, followed by HLA-A, then HLA-C.