ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
Which of the following is used to characterize antigens in complex mixtures biochemically?
Correct Answer: D
Rationale: Western blotting separates proteins by size and uses antibodies to characterize antigens biochemically in complex mixtures.
Question 2 of 5
Protein and nucleic acid sequence data have been obtained for many TCRs with different specificities. Analyses of these sequences suggest the existence of how many hypervariable (hv) regions within the variable region?
Correct Answer: C
Rationale: TCRs have three hypervariable regions (CDR1, CDR2, CDR3) within their variable regions, similar to immunoglobulins.
Question 3 of 5
Deficiencies in lead to autosomal-recessive severe combined immunodeficiency disease (SCID).
Correct Answer: C
Rationale: Deficiencies in either RAG-1 or RAG-2 can cause SCID due to impaired V(D)J recombination.
Question 4 of 5
Adhesion molecule
Correct Answer: D
Rationale: CD11a (LFA-1) is an adhesion molecule that stabilizes T cell interactions.
Question 5 of 5
Which of the following MHC class II genes has the most alleles (most polymorphic)?
Correct Answer: D
Rationale: DRβ is the most polymorphic among MHC class II genes.