ATI RN
Test Bank Pharmacology Questions
Question 1 of 4
Which of the following is the only medication that is approved for the management of amyotrophic lateral sclerosis?
Correct Answer: D
Rationale: Riluzole is the only FDA-approved drug for ALS, extending survival by inhibiting glutamate release, reducing excitotoxicity that accelerates motor neuron death. It modestly slows progression, offering a disease-modifying effect. Pramipexole and selegiline, dopamine-related drugs, treat Parkinson's, not ALS. Galantamine, a cholinesterase inhibitor, targets Alzheimer's cognition. Glatiramer manages MS via immune modulation. Riluzole's glutamate antagonism addresses ALS's neurodegenerative mechanism, backed by clinical trials, making it uniquely approved for this fatal condition.
Question 2 of 4
The patient has a potassium level of 5.9 mEq/L. The nurse is administering glucose and insulin. The patient's wife says, 'He doesn't have diabetes, why is he getting insulin?' What is the best response by the nurse?
Correct Answer: A
Rationale: In hyperkalemia (5.9 mEq/L), insulin shifts potassium into cells , lowering serum levels temporarily, paired with glucose to avoid hypoglycemia. Choice B misstates excretion. Choice C compares unnecessarily. Choice D attributes renal action incorrectly. A explains the mechanism accurately, making it the best response.
Question 3 of 4
A client with gout is prescribed allopurinol (Zyloprim). Which laboratory value should the nurse monitor?
Correct Answer: A
Rationale: Allopurinol reduces uric acid production, treating gout by inhibiting xanthine oxidase. Monitoring serum uric acid tracks efficacy, ensuring levels drop (normal: 3.5-7.2 mg/dL) to prevent flares. BUN reflects kidney function, relevant but secondary unless damage exists. White blood cells and platelets aren't directly affected unless hypersensitivity occurs (rare). Uric acid is the therapeutic target, aligning with allopurinol's mechanism, critical in gout where hyperuricemia drives symptoms. Regular checks confirm treatment success, guiding dose adjustments, making A the key value to monitor.
Question 4 of 4
The following drugs are contraindicated in asthma:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.