Which of the following is the only medication that is approved for the management of amyotrophic lateral sclerosis?

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ATI Proctored Pharmacology 2023 Quizlet Questions

Question 1 of 5

Which of the following is the only medication that is approved for the management of amyotrophic lateral sclerosis?

Correct Answer: D

Rationale: Riluzole is the only FDA-approved drug for ALS, extending survival by inhibiting glutamate release, reducing excitotoxicity that accelerates motor neuron death. It modestly slows progression, offering a disease-modifying effect. Pramipexole and selegiline, dopamine-related drugs, treat Parkinson's, not ALS. Galantamine, a cholinesterase inhibitor, targets Alzheimer's cognition. Glatiramer manages MS via immune modulation. Riluzole's glutamate antagonism addresses ALS's neurodegenerative mechanism, backed by clinical trials, making it uniquely approved for this fatal condition.

Question 2 of 5

A child is receiving methylphenidate. The mother tells the nurse the patient is having trouble sleeping while on the medication. What is the best response by the nurse?

Correct Answer: A

Rationale: Methylphenidate, a stimulant used to treat ADHD, can cause insomnia if taken too late in the day. Administering the medication earlier in the day (before 4:00 pm) can help minimize sleep disturbances. Giving it at 8:00 pm (B) would worsen insomnia. Stopping the medication abruptly (C) is not recommended without consulting the healthcare provider. Diphenhydramine (D) is not a solution for stimulant-induced insomnia.

Question 3 of 5

A patient was prescribed sertraline (Zoloft) for the treatment of depression and anxiety. The patient's spouse calls the clinic and reports the patient is increasingly moody and seems 'disconnected with life.' What is the best response by the nurse?

Correct Answer: B

Rationale: Worsening mood and disconnection on sertraline signal risk-e.g., suicidal ideation, per SSRI warnings-needing urgent clinic assessment. Benadryl is inappropriate-sedation won't fix. Holding meds risks withdrawal. Doubling dose escalates danger. Immediate evaluation ensures safety, per protocol.

Question 4 of 5

Protamine Sulfate is known to counteract the therapeutic effect of which medication?

Correct Answer: B

Rationale: Protamine sulfate is commonly used as an antidote for heparin overdose. Heparin is an anticoagulant medication given to prevent blood clots, but in cases of excessive bleeding or overdose, protamine sulfate can be administered to counteract its effects. Therefore, it is important to be aware that protamine sulfate can negate the therapeutic effect of heparin.

Question 5 of 5

Which of the following is the antidote for Heparin?

Correct Answer: A

Rationale: Protamine sulfate is the antidote for Heparin. Heparin is an anticoagulant medication that works by inhibiting the clotting factors in the blood. In cases of Heparin overdose or when there is a need to reverse its anticoagulant effects quickly, protamine sulfate can be administered. Protamine sulfate binds to Heparin and neutralizes its anticoagulant effects, making it an effective antidote. It is important to administer the antidote under the guidance of a healthcare professional to prevent any adverse reactions.

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