Which of the following is the main immunoglobulin in the gut and secretions (saliva, milk, tears) and is important in mucosal immunity?

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Pediatric Immunity NCLEX Questions Questions

Question 1 of 5

Which of the following is the main immunoglobulin in the gut and secretions (saliva, milk, tears) and is important in mucosal immunity?

Correct Answer: A

Rationale: IgA predominates in mucosal areas and secretions, providing local immunity.

Question 2 of 5

During the final step of synthesis for heavy and light immunoglobulin chains, which of the following peptides is cleaved?

Correct Answer: A

Rationale: The Leader (L) peptide is cleaved during the final processing of immunoglobulin chains to produce the mature protein.

Question 3 of 5

Where are δγ T cells generally found in the body (location of TCR rearrangement)?

Correct Answer: D

Rationale: TCR rearrangement for δγ T cells occurs in the thymus, where T cell development takes place.

Question 4 of 5

If a B cell successfully rearranges the first heavy chain locus, it inhibits the rearrangement of the other heavy chain on the other chromosome. What is this called?

Correct Answer: B

Rationale: Allelic exclusion prevents rearrangement of the second allele after a successful first rearrangement.

Question 5 of 5

Involved in signal transduction on different T cells

Correct Answer: B

Rationale: CD3 is involved in signal transduction across all T cells.

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