Which of the following is required for a CD8+ cell to differentiate into an effector cytotoxic T cell (CTL)? Is this a physical interaction?

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 5

Which of the following is required for a CD8+ cell to differentiate into an effector cytotoxic T cell (CTL)? Is this a physical interaction?

Correct Answer: D

Rationale: CD8+ differentiation requires antigen recognition and CD4+ TH costimulation, involving physical interaction.

Question 2 of 5

What type of cells produce type I interferons (IFN-α and IFN-β)?

Correct Answer: C

Rationale: Plasmacytoid dendritic cells are the primary producers of type I interferons.

Question 3 of 5

The membrane attack complex (MAC) uses C3 to activate the final part of the complement pathway. It is important in defense against Neisseria. Which of the following components is/are inserted into the plasma membrane of the target cell, allowing for free passage of water/solute and thus killing the cell?

Correct Answer: D

Rationale: C5b-C9 form the MAC, with C9 polymerizing to lyse the target cell.

Question 4 of 5

Increases marrow production of neutrophils

Correct Answer: C

Rationale: G-CSF stimulates neutrophil production in bone marrow.

Question 5 of 5

Increases vascular permeability

Correct Answer: B

Rationale: Histamine, released by mast cells, increases vascular permeability, aiding immune cell infiltration to the site of infection.

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