ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
Which of the following is NOT true regarding live viral vectored vaccines?
Correct Answer: A
Rationale: Live viral vectored vaccines mimic infection and don't typically require adjuvants, unlike subunit vaccines.
Question 2 of 5
A patient presents at age 6-months with pneumonia and difficulty fighting off infections of encapsulated bacteria and enteroviruses. A mutation in Bruton's tyrosine kinase (btk) is suspected. Which of the following is the most likely?
Correct Answer: C
Rationale: X-linked agammaglobulinemia, due to BTK mutations, causes B cell deficiency and infections with encapsulated bacteria.
Question 3 of 5
This parasite (Onchcerca volvulus) lives outside its host's cells (extracellular); therefore, cytotoxic T cells (CTLs) are ineffective in clearing the organism. This inability on the part of CTLs is due to their requirement to engage which of the following surface structures for their cytotoxic activity?
Correct Answer: B
Rationale: Cytotoxic T cells (CTLs) target intracellular pathogens by recognizing antigens presented on MHC class I molecules. Since Onchocerca volvulus is extracellular, CTLs are ineffective as they cannot engage MHC class I-peptide complexes in this context.
Question 4 of 5
Which of the following is expressed by tumor cells to suppress T cells?
Correct Answer: D
Rationale: PD-L1 (Programmed Death-Ligand 1) is expressed by tumor cells to bind PD-1 on T cells, suppressing their activity and enabling immune evasion.
Question 5 of 5
Which of the following have not provided examples of secondary immunodeficiency?
Correct Answer: D
Rationale: High fat diet is not a well-documented cause of secondary immunodeficiency, unlike viral infections (e.g., HIV), lymphoproliferative disorders, or cytotoxic drugs.