Which of the following is not true in thrombasthenia:

Correct Answer: D

Rationale: In thrombasthenia, there is a deficiency or dysfunction of integrin αIIbβ3 (GPIIb/IIIa), leading to impaired platelet aggregation. Prolonged bleeding time (A) is seen due to defective platelet function. Platelet count (B) is typically normal as thrombasthenia does not affect platelet production. Platelet aggregation defect (C) is a characteristic feature of thrombasthenia. Prolonged clotting time (D) is not associated with thrombasthenia as it primarily affects platelet function, not the coagulation cascade. Hence, choice D is the correct answer.

Correct Answer: A

Rationale: The correct answer is A: hyperchlorhydria. Pernicious anemia is characterized by vitamin B12 deficiency due to impaired absorption, not excess stomach acid. Premature graying of hair is unrelated. Presence of anti-intrinsic factor antibody and risk of gastric polyps are associated with pernicious anemia, but not hyperchlorhydria. Therefore, choice A is the correct answer as it does not align with the typical symptoms and characteristics of pernicious anemia.

Correct Answer: D

Rationale: Plat. transfusion is not indicated in immunogenic thrombocytopenia (ITP) because it is an autoimmune disorder where the body destroys its own platelets. Transfusing platelets won't solve the underlying issue of platelet destruction. In aplastic anemia (A), platelet transfusion can help due to low platelet production. In uremia with bleeding (B) and DIC (C), platelet transfusion is necessary to manage bleeding due to decreased platelet function or consumption.

Correct Answer: D

Rationale: The correct answer is D: CML. Peripheral blood picture is most useful in CML because it typically shows increased white blood cell count with left shift, basophilia, and presence of the Philadelphia chromosome. In contrast, A (NHL) primarily involves lymph nodes, B (multiple myeloma) shows monoclonal protein in serum/bone marrow, and C (myelodysplastic syndrome) presents with cytopenias and dysplastic changes in blood cells. Therefore, based on the specific findings seen in CML on peripheral blood, it is the most appropriate choice.

Correct Answer: C

Rationale: The correct answer is C because it demonstrates empathy and support. By asking if the patient would like the nurse to sit with him, it shows willingness to provide comfort and assistance. This action allows the patient to feel supported while expressing his feelings. Choice A is incorrect because leaving the patient alone may make him feel abandoned. Choice B is not the most immediate action needed in this situation. Choice D is incorrect because it assumes understanding without actively offering support.