Which of the following is not directly related to drug toxicity of Nitroglycerin?

Correct Answer: D

Rationale: The correct answer is D: Projectile vomiting. Nitroglycerin is not directly associated with causing projectile vomiting. Nitroglycerin commonly causes headaches due to vasodilation, tachycardia due to decreased preload, and dizziness due to hypotension. Projectile vomiting is not a typical side effect of Nitroglycerin toxicity.

Correct Answer: A

Rationale: The correct answer is A: Hypertension is not a side effect of Sympathoplegics (Clonidine). Sympathoplegics are medications that inhibit the sympathetic nervous system, leading to decreased heart rate and blood pressure. Therefore, hypertension is not a common side effect. Choices B, C, and D are incorrect because difficulty breathing, dry oral cavity, and lethargic behavior are potential side effects of Sympathoplegics due to their central nervous system depressant effects.

Correct Answer: C

Rationale: The correct answer is C: Tetracycline. Tetracycline is associated with extreme photosensitivity due to its mechanism of action causing phototoxic reactions when exposed to sunlight. Digitalis (A) is a cardiac medication, niacin (B) is a B vitamin, and fluoroquinolones (D) are antibiotics, none of which are known to cause extreme photosensitivity reactions.

Correct Answer: A

Rationale: The correct answer is A: Renal disease. Epinephrine is not used to treat renal disease because it can potentially worsen kidney function. Epinephrine is used in asthma to dilate the airways, in hypotension to increase blood pressure, and in glaucoma to reduce intraocular pressure. Treating renal disease with epinephrine can lead to further complications due to its effect on blood flow and kidney function. Therefore, renal disease is not treated with epinephrine to avoid exacerbating kidney issues.

Correct Answer: D

Rationale: The correct answer is D: Muscle wasting. Ibuprofen is primarily associated with gastrointestinal side effects like nausea, renal dysfunction, and anemia due to its effects on the stomach, kidneys, and blood. Muscle wasting is not a known direct effect of Ibuprofen toxicity. Ibuprofen is not typically linked to muscle-related issues, making choice D the correct answer.

Correct Answer: D

Rationale: Step 1: Ethosuximide is the correct answer as it is a known trigger for Stevens-Johnson syndrome due to its association with hypersensitivity reactions. Step 2: Valproic acid can cause liver toxicity but is not typically linked to Stevens-Johnson syndrome. Step 3: Quinidine is associated with drug-induced lupus but not commonly known to cause Stevens-Johnson syndrome. Step 4: Isoniazid is linked to drug-induced hepatitis but not typically associated with Stevens-Johnson syndrome. In summary, Ethosuximide is the correct choice due to its well-documented association with Stevens-Johnson syndrome, while the other options are linked to different adverse effects.

Correct Answer: B

Rationale: Prednisone is a corticosteroid used to treat inflammatory conditions and certain types of cancer. Testicular cancer is not typically treated with Prednisone because it is a form of cancer that requires specific treatments such as surgery, chemotherapy, or radiation therapy. Prednisone is not the primary treatment option for testicular cancer. In contrast, Prednisone is commonly used to manage symptoms in conditions like Cushing's disease, lymphomas, and chronic leukemias by reducing inflammation and suppressing immune response. Therefore, choice B is the correct answer as Prednisone is not a standard treatment for testicular cancer.

Correct Answer: B

Rationale: The correct answer is B: Nausea. Loop diuretics like furosemide work by inhibiting the reabsorption of sodium and water in the loop of Henle in the kidneys. This mechanism can lead to electrolyte imbalances, such as potassium deficits (choice D), and volume depletion, resulting in hypotension (choice C). Loop diuretics can also cause metabolic alkalosis (choice A) due to loss of hydrogen ions. Nausea, however, is not a common side effect of loop diuretics. Therefore, choice B is not a side effect of loop diuretics, making it the correct answer.

Correct Answer: B

Rationale: Barbiturates are central nervous system depressants used to treat seizures, insomnia, and anxiety. However, they can worsen hypotension as they can cause vasodilation and decrease blood pressure. Choice B is correct because using barbiturates in hypotensive patients can lead to further lowering of blood pressure, potentially causing harm. Choices A, C, and D are incorrect as barbiturates are commonly used to treat seizures, insomnia, and anxiety, respectively, due to their sedative and anticonvulsant properties.