ATI RN
ATI RN Pharmacology Proctored Exam 2023 Questions
Question 1 of 5
Which of the following is NOT a therapeutic effect of Montelukast?
Correct Answer: D
Rationale: Montelukast is a medication commonly used to treat asthma and allergic rhinitis. Its therapeutic effects include decreased frequency and severity of acute asthma attacks, decreased severity of allergic rhinitis, and decreased attacks of exercise-induced bronchoconstriction. However, Montelukast is not associated with treating anxiety attacks. Anxiety is a mental health condition that is typically managed with appropriate therapy and medication specifically designed for anxiety disorders.
Question 2 of 5
A patient is receiving heparin therapy as part of the treatment for a pulmonary embolism. The nurse monitors the results of which laboratory test to check the drug™s effectiveness?
Correct Answer: B
Rationale: The nurse monitors the aPTT to check the effectiveness of heparin therapy in preventing and treating blood clots. Heparin acts by inhibiting the clotting cascade, specifically by enhancing the activity of antithrombin III, which inactivates clotting factors such as thrombin and factor Xa. The aPTT measures the intrinsic pathway of the clotting cascade, which is affected by heparin therapy. By monitoring the patient's aPTT levels, the nurse can ensure that the patient is within the therapeutic range for heparin therapy to be effective in preventing further clot formation. Monitoring bleeding times, PT/INR, or vitamin K levels is not typically done to assess heparin therapy effectiveness.
Question 3 of 5
A woman who wishes to become pregnant is concerned about the drugs she must take in order to treat a serious medical condition. The nurse reviewing the drug list would be most concerned about which kind of drug?
Correct Answer: A
Rationale: Long half-life drugs (e.g., diazepam) linger, risking fetal exposure post-conception, a pharmacokinetic worry for serious conditions. No active metabolites reduce risk. High protein-binding limits free drug, less concern. As-needed use minimizes exposure. Long half-life heightens teratogenic potential, critical in planning.
Question 4 of 5
A patient has received an overdose of intravenous heparin, and is showing signs of excessive bleeding. Which substance is the antidote for heparin overdose?
Correct Answer: C
Rationale: Protamine sulfate is the antidote for heparin overdose. Heparin is an anticoagulant medication that works by inhibiting the action of thrombin and factor Xa. Protamine works by binding to heparin and neutralizing its anticoagulant effects. This helps to reverse the effects of heparin and control excessive bleeding in cases of overdose. It is important to administer protamine sulfate promptly to counteract the effects of heparin and prevent further bleeding complications. Options A, B, and D are not the correct antidotes for heparin overdose.
Question 5 of 5
Which of the following antipsychotic agents is available in a LAI formulation that may be useful for patients with difficulty adhering to therapy?
Correct Answer: D
Rationale: Risperidone, a second-generation antipsychotic, offers a long-acting injectable (LAI) formulation (e.g., Risperdal Consta), administered every two weeks, improving adherence in schizophrenia patients with poor oral compliance. Asenapine is sublingual, not LAI. Chlorpromazine, a first-generation drug, lacks an LAI form. Clozapine, effective for treatment-resistant cases, is oral only due to agranulocytosis monitoring. Quetiapine has no LAI. Risperidone's LAI ensures steady drug levels, reducing relapse risk, making it ideal for adherence challenges, per clinical use.