Which of the following is NOT a symptom of Addison’s disease?

Correct Answer: B

Rationale: The correct answer is B: Weight gain. Addison's disease is characterized by adrenal insufficiency, leading to symptoms such as salt craving, hypoglycemia, and hyperpigmentation due to increased melanin production. Weight loss, not weight gain, is commonly associated with Addison's disease due to decreased cortisol levels. Salt craving is due to sodium loss, hypoglycemia results from insufficient cortisol levels, and hyperpigmentation is caused by elevated ACTH levels stimulating melanin production. Weight gain is not a typical symptom, making it the correct answer.

Correct Answer: A

Rationale: Aldosterone is the correct answer because it specifically acts on the kidneys to increase the reabsorption of sodium. It is produced by the adrenal glands in response to low blood pressure or low sodium levels. Aldosterone binds to receptors in the kidneys, leading to increased sodium reabsorption and potassium excretion. Angiotensin plays a role in stimulating the release of aldosterone, but it does not directly affect sodium reabsorption. ADH regulates water reabsorption, not sodium. ACTH stimulates the adrenal glands to produce cortisol, not aldosterone. Therefore, aldosterone is the hormone responsible for the reabsorption of sodium in the kidneys.

Correct Answer: B

Rationale: The correct answer is B because free fatty acid mobilization is primarily regulated by cortisol, not dehydroepiandrosterone. Cortisol promotes lipolysis and stimulates the release of free fatty acids from adipose tissue. Dehydroepiandrosterone is a precursor hormone mainly involved in sex hormone production and has minimal effects on free fatty acid mobilization. Choices A, C, and D are correctly paired as gluconeogenesis is stimulated by cortisol, muscle glycogenolysis is regulated by epinephrine, and kaliuresis is induced by aldosterone.

Correct Answer: B

Rationale: The correct answer is B: controls the amount of urine one produces. Antidiuretic hormone (ADH) acts on the kidneys to regulate water reabsorption, thereby controlling the amount of urine produced. It does not control metabolic rate (A), increase blood sugar (C), or control reproduction (D). ADH's main function is to maintain water balance in the body by reducing urine output.

Correct Answer: B

Rationale: The correct answer is B: Thyroid. The body's major metabolic hormone, thyroxine (T4) and triiodothyronine (T3), is released from the thyroid gland. The thyroid gland plays a crucial role in regulating metabolism. Pituitary (A) releases various hormones but not the major metabolic hormone. Thymus (C) is responsible for immune function, not metabolism. Hypothalamus (D) regulates the pituitary gland but does not directly release the major metabolic hormone.