ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 5
Which of the following is NOT a site for drug metabolism:
Correct Answer: D
Rationale: The placenta is not a site for drug metabolism. Drug metabolism primarily occurs in the liver, gastrointestinal tract (GIT), skin, and kidney. The placenta serves as a barrier between the mother and fetus and is involved in nutrient and waste exchange but does not play a significant role in drug metabolism processes.
Question 2 of 5
A patient who has been diagnosed with social anxiety disorder will begin taking venlafaxine(Effexor). The nurse who performs a medication and dietary history will be concerned about ingestion of which substance or drug?
Correct Answer: D
Rationale: St. John's wort is an herbal supplement that can interact with many medications, including venlafaxine (Effexor). When taken together, it can decrease the effectiveness of venlafaxine by increasing its metabolism, potentially leading to reduced therapeutic effects. This interaction can also increase the risk of side effects or adverse reactions. Therefore, the nurse should be concerned about the ingestion of St. John's wort when a patient is taking venlafaxine to ensure proper medication management and effectiveness. It is important for patients to inform healthcare providers about all supplements they are taking to prevent harmful interactions.
Question 3 of 5
Which activity has a higher priority for the nurse to advise the patient to avoid while taking ixazomib?
Correct Answer: C
Rationale: Ixazomib, a proteasome inhibitor, can cause myelosuppression, increasing the risk of infections. Patients should be advised to avoid crowds and individuals who are ill to reduce exposure to infectious agents. While alcohol and aspirin may interact with other medications, they are not specifically contraindicated with ixazomib. Taking the drug on an empty stomach is not required, as it can be taken with or without food. Preventing infections is the highest priority due to the drug's impact on the immune system.
Question 4 of 5
A male patient is to begin therapy with isotretinoin and asks, 'What do I have to remember to do while taking this medicine?' How would the nurse respond? (Select all that apply.)
Correct Answer: B
Rationale: Isotretinoin is a potent medication with significant side effects and precautions. Patients should avoid sunlight (A) due to increased photosensitivity. Regular laboratory tests (C) are necessary to monitor liver function and lipid levels. Two forms of contraceptives (D) are required for females due to the high risk of teratogenicity. Monitoring weight (B) is not typically associated with isotretinoin use.
Question 5 of 5
An elderly woman took a prescription medicine to help her to sleep; however, she felt restless all night and did not sleep at all. The nurse recognizes that this woman has experienced which type of reaction or effect?
Correct Answer: B
Rationale: An idiosyncratic reaction is an unusual or unexpected response to a medication that is not related to the drug's known pharmacological effects. In this case, the elderly woman experienced restlessness instead of sedation, which is contrary to the expected effect of a sleep aid. Idiosyncratic reactions are unpredictable and can vary widely among individuals. Allergic reactions involve the immune system, mutagenic effects involve genetic changes, and synergistic effects involve interactions between multiple drugs. Since the woman's response was unexpected and not consistent with the drug's intended effect, it is classified as an idiosyncratic reaction.