ATI RN
ATI Pharmacology Study Guide Questions
Question 1 of 5
Which of the following is NOT a pharmacologic property of histamine:
Correct Answer: D
Rationale: Histamine is a biogenic amine that acts as a neurotransmitter in the body. It is known to have several pharmacologic properties, such as the ability to reduce gastric secretion (Choice A), relaxation of vascular smooth muscle (Choice B), contraction of bronchi (Choice C), and production of pain and itch (Choice E). However, histamine does not have a direct effect on free nerve endings. Its effects on pain and itch are mediated through activation of specific histamine receptors on nerve cells and not through direct action on free nerve endings.
Question 2 of 5
An important function of calcium is to
Correct Answer: D
Rationale: Calcium regulates nerve transmission-e.g., neurotransmitter release, per physiology-not acid-base (HCO3-), glucose (insulin), or energy (ATP). Nerve function is key, per role.
Question 3 of 5
Bioavailability is:
Correct Answer: D
Rationale: Bioavailability can be 100% (e.g., IV), not always less, so that's false. It's the fraction reaching systemic circulation, not just absorbed, making that incomplete. First-pass metabolism reduces bioavailability, so that's false. Verapamil's oral bioavailability is low (~20-35%), not 80%, due to extensive first-pass metabolism, but the key indicates this as true (possibly a typo; typically false). The correct interpretation aligns with bioavailability as absorption minus extraction, though the key's choice needs context. Verapamil's low bioavailability informs its dosing.
Question 4 of 5
A client is prescribed an intranasal corticosteroid. What should the nurse include in client education about this drug?
Correct Answer: D
Rationale: Intranasal corticosteroids (e.g., fluticasone) can cause burning and nosebleeds due to mucosal drying . They're preventive, not symptom-driven (choice B is wrong), and dosing is fixed, not squeeze-dependent . Choice D educates on a common, manageable side effect, ensuring client awareness and compliance.
Question 5 of 5
A male patient needs to receive a unit of whole blood. What type of intravenous (IV) device should the nurse consider starting?
Correct Answer: C
Rationale: A large-bore catheter is recommended for whole blood transfusions to allow for the rapid administration of blood products and to prevent hemolysis. Smaller catheters may not accommodate the viscosity of whole blood and could increase the risk of complications. While patient comfort and past experiences are important, the primary consideration is the safe and effective delivery of the transfusion. Therefore, a large-bore catheter is the best choice.