ATI RN
ATI Practice Exam Pharmacology The Endocrine System Questions
Question 1 of 5
Which of the following is least likely to have an adverse drug interaction with phenelzine (a monoamine oxidase (MAO) inhibitor)?
Correct Answer: D
Rationale: Phenelzine, an MAOI, risks hypertensive crisis or serotonin syndrome with drugs increasing monoamines. Levodopa raises catecholamines, risking hypertension with MAOIs. Ropinirole, a dopamine agonist, may enhance monoamine effects, potentially hazardous. Tolcapone, a COMT inhibitor, increases levodopa levels, amplifying MAOI risks. Pseudoephedrine, a sympathomimetic, causes severe hypertension. Propofol, an anesthetic, acts via GABA without monoamine interaction, making it least likely to cause adverse effects with phenelzine. Its safety profile here is key for procedural use in MAOI patients.
Question 2 of 5
A client with benign prostatic hyperplasia is to receive finasteride (Proscar). The nurse understands that this drug works by
Correct Answer: B
Rationale: Finasteride (Proscar), a 5-alpha reductase inhibitor, reduces prostate size in benign prostatic hyperplasia (BPH) by blocking dihydrotestosterone (DHT) production, shrinking glandular tissue and easing urinary obstruction. Relaxing penile smooth muscle is the role of phosphodiesterase-5 inhibitors like sildenafil, not finasteride. It lowers DHT, not testosterone, and may even slightly increase circulating testosterone, but that's not its aim. Stimulating RNA synthesis relates to androgens' anabolic effects, not finasteride's mechanism. Shrinking the prostate is its core function, taking months to reduce symptoms, distinct from acute smooth muscle relaxation or hormonal boosts, aligning with BPH management goals.
Question 3 of 5
Enzymatic activity that changes a medication into a less active form is an example of
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
The patient tells the nurse that she is interested in the human brain and questions which parts of the brain control anxiety and insomnia. What is the best reply by the nurse?
Correct Answer: A
Rationale: The limbic system (e.g., amygdala) drives anxiety-emotional response-while the reticular activating system (RAS) regulates sleep-wake, impacting insomnia, per neuroanatomy. Frontal lobes plan, not directly control these. Thalamus relays, not initiates. Hypothalamus affects sleep but less anxiety. Limbic-RAS pairing fits, answering precisely.
Question 5 of 5
The nurse has taught the client with osteoporosis about how to manage the illness. Which statement by the client indicates that additional teaching is necessary?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.