ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
Which of the following is expressed by tumor cells to suppress T cells?
Correct Answer: D
Rationale: PD-L1 (Programmed Death-Ligand 1) is expressed by tumor cells to bind PD-1 on T cells, suppressing their activity and enabling immune evasion.
Question 2 of 5
Which of the following isotypes of antibodies activate the complement cascade if bound to antigen?
Correct Answer: D
Rationale: IgM and IgG effectively activate the complement cascade via the classical pathway when bound to antigens.
Question 3 of 5
An article published in the Oncoimmunology journal in September 2018. It is discussing an immunotherapy approach that relies on designing and infecting the cancer patient two viruses expressing Melanoma-associated antigen A3 (MAGE-A3). The two viruses, a replication-deficient type-5 human adenoviral (Ad-MAGEA3) and Maraba MGI rhabdovirus(MGI-MAGEA3), are studied in this article preclinically by infecting nonhuman primates(monkeys). This immunotherapy approach is considered:
Correct Answer: A
Rationale: Using viruses to express tumor antigens like MAGE-A3 to stimulate an immune response classifies this as a vaccination strategy in cancer immunotherapy.
Question 4 of 5
Matching: Complement deficiency - Nonpitting edema
Correct Answer: D
Rationale: C1 inhibitor deficiency causes hereditary angioedema, characterized by nonpitting edema due to unregulated bradykinin production. Other complement deficiencies do not typically present with this feature.
Question 5 of 5
Matching: Immunodeficiency - Elevated IgE levels and eosinophilia
Correct Answer: D
Rationale: Hyper-IgE syndrome is defined by elevated IgE and eosinophilia, alongside recurrent infections and skin findings.