ATI RN
Intro to Pharmacology ATI Quizlet Questions
Question 1 of 4
Which of the following is defined as the least stimulus intensity at which a subject perceives pain?
Correct Answer: A
Rationale: The pain threshold is defined as the least stimulus intensity at which a subject perceives pain. It represents the point at which a person first acknowledges experiencing pain. Pain threshold varies among individuals and can be influenced by various factors such as genetics, emotional state, culture, and past experiences with pain. It is an important concept in understanding an individual's sensitivity to pain and can be different from their pain tolerance level, which refers to the maximum level of pain a person is willing to endure. Analgesia involves the relief of pain, nociception is the body's physiological response to noxious stimuli, and polymodal refers to nerve fibers that respond to multiple types of stimuli.
Question 2 of 4
The patient takes labetalol and is scheduled for surgery. The anesthesiologist plans to use halothane as one of the anesthetic agents. The nurse consults with the anesthesiologist to ensure awareness the patient’s medication history knowing that the combination of labetalol and halothane will have what effect?
Correct Answer: A
Rationale: There is increased risk of excessive hypotension if any of these drugs is combined with volatile liquid general anesthetics such as enflurane, halothane, or isoflurane. The effectiveness of diabetic agents is increased, leading to hypoglycemia when such agents are used with these drugs. Carvedilol has been associated with potentially dangerous conduction system disturbances when combined with verapamil or diltiazem. Vomiting is not associated with this combination of drugs. The nurse should communicate the patient’s medication history to the anesthesiologist to ensure safe administration of anesthesia.
Question 3 of 4
A patient is taking ibuprofen. The nurse understands that COX-1 and COX-2 inhibitors are different in that ibuprofen is more likely than celecoxib to cause which adverse effect?
Correct Answer: C
Rationale: Ibuprofen is a non-selective COX inhibitor, meaning it inhibits both COX-1 and COX-2 enzymes. COX-1 is responsible for maintaining the protective lining of the stomach, and its inhibition can lead to gastrointestinal adverse effects such as peptic ulcer disease. Celecoxib, on the other hand, is a selective COX-2 inhibitor, which primarily targets inflammation and pain without significantly affecting the stomach lining. Therefore, ibuprofen is more likely to cause peptic ulcer disease compared to celecoxib. This distinction is crucial for nurses to understand when managing patients on these medications, as it impacts patient monitoring and education.
Question 4 of 4
The nurse is reviewing the client's history who is about to take Methotrexate. Which of the following drugs can be safely administered together with methotrexate?
Correct Answer: B
Rationale: Folic acid supplementation is recommended for patients on methotrexate to reduce the risk of side effects such as mucositis and myelosuppression. Tetracycline, sulfamethoxazole, and phenytoin can interact with methotrexate, increasing its toxicity. Folic acid helps mitigate these adverse effects without interfering with the drug's efficacy.