Which of the following is an active transport mechanism?

Correct Answer: D

Rationale: The correct answer is D: pinocytosis. This is an active transport mechanism where cells engulf fluids or solutes through vesicles. Energy is required to transport substances against a concentration gradient. A is incorrect as pinocytosis is an active process, not passive like pinocytosis. B is incorrect as facilitated diffusion is a passive process that uses carrier proteins to move substances down a concentration gradient. C is incorrect as filtration is a passive process that relies on pressure gradients to move substances across a barrier. Therefore, D is the correct choice as it involves the active transport of substances into the cell.

Correct Answer: B

Rationale: The correct answer is B: EBV. Osteomyelitis is primarily caused by bacteria, not viruses like Epstein-Barr virus (EBV). The main pathogens involved in osteomyelitis are typically Staphylococcus aureus, including Methicillin-resistant Staphylococcus aureus (MRSA), Haemophilus influenzae, and Pseudomonas aeruginosa. EBV is not a causative agent of osteomyelitis. It is crucial to differentiate between bacterial and viral etiologies in infectious diseases to guide appropriate treatment.

Correct Answer: D

Rationale: The correct answer is D because the rubella virus has icosahedral symmetry, meaning it has a spherical shape with 20 equilateral triangular faces. This symmetry is common in many viruses and allows for efficient packaging of genetic material. Choice A is incorrect because the rubella virus does have glycoprotein spikes on its surface. These spikes help the virus attach to host cells. Choice B is incorrect because the rubella virus does have an envelope derived from the host cell membrane. This envelope plays a role in viral entry into host cells. Choice C is incorrect because the rubella virus is an ssRNA virus, not ssDNA. Its genetic material is single-stranded RNA, not DNA. In summary, the rubella virus has icosahedral symmetry and possesses glycoprotein spikes, an envelope, and ssRNA genetic material, making choices A, B, and C incorrect.

Correct Answer: C

Rationale: The correct answer is C: Up to 3 months. Hepatitis B has an average incubation period of 60-90 days, which aligns with the timeframe of up to 3 months. This period refers to the time between exposure to the virus and the onset of symptoms. One week to 10 days (choice A) is too short for hepatitis B, as it typically takes longer to manifest. One month to 45 days (choice B) is also shorter than the average incubation period for hepatitis B. Up to 6 months (choice D) is too long for hepatitis B, as the virus typically shows symptoms within 3 months.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. This is because Streptococcus pyogenes is a Gram-positive cocci in chains bacterium that is catalase-negative, making it the most likely causative agent in this scenario. Streptococcus pyogenes is a common pathogen causing bacterial endocarditis. Summary of other choices: B: Staphylococcus aureus is a Gram-positive cocci bacterium but is catalase-positive, so it is unlikely in this case. C: Enterococcus faecalis is a Gram-positive cocci bacterium, but it is catalase-negative, which is not consistent with the given information. D: Micrococcus luteus is a Gram-positive cocci bacterium but is catalase-positive, making it an unlikely causative agent.

Correct Answer: C

Rationale: The correct answer is C: Erysipelas. Erysipelas is a type of acute infection caused by group A Streptococcus bacteria. This bacteria infects the upper dermis and superficial lymphatics, leading to a distinct raised, well-demarcated, erythematous skin lesion. The other choices are incorrect because: A Carbuncle is a deep skin infection involving hair follicles, B Impetigo is a superficial skin infection caused by Staphylococcus or Streptococcus bacteria, and D Acne is a chronic inflammatory skin condition not typically caused by group A Streptococcus.

Correct Answer: B

Rationale: The Ziehl-Neelsen stain is specifically designed to detect acid-fast bacteria like Mycobacterium tuberculosis. It utilizes a carbol fuchsin dye that binds to the high lipid content in the cell wall of acid-fast bacteria, making them appear red under a microscope. This staining method is crucial for the diagnosis of tuberculosis and leprosy. Gram-positive bacteria (Choice A) are not detected by this stain since they have a different cell wall structure. Capsulated bacteria (Choice C) and fungal spores (Choice D) also have distinct characteristics that are not targeted by the Ziehl-Neelsen stain.

Correct Answer: C

Rationale: The correct answer is C: Binding of mast cell-fixed IgE. The Bezredka method involves introducing small amounts of the antigen to which the individual is allergic, leading to the binding of mast cell-fixed IgE. This process desensitizes the immune system and prevents anaphylactic shock by reducing the release of histamine and other mediators from mast cells. Rationale: 1. A: Stimulation of antigen-specific IgG2 is incorrect because the Bezredka method primarily targets IgE, not IgG2. 2. B: Stimulation of the immunological antigen tolerance is incorrect as this method aims to block the allergic response rather than induce tolerance. 3. D: Blocking of mast cell mediators synthesis is incorrect because the Bezredka method does not directly inhibit the synthesis of mast cell mediators, but rather blocks their release by binding IgE.

Correct Answer: D

Rationale: The correct answer is D, as all options A, B, and C are determinants of antigenicity. A: Chemical nature influences how the immune system recognizes antigens. B: The size of the antigen affects its ability to be recognized by immune cells. C: Antigens of foreign origin are more likely to trigger an immune response. Therefore, all of these factors together play a crucial role in determining antigenicity.