ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
Which of the following is a large genomic region or gene family found in most vertebrates, playing an important role in immunity?
Correct Answer: B
Rationale: MHCs are a large gene family in vertebrates critical for presenting antigens to T cells, distinguishing them from HLAs (a subset of MHC in humans) and other options.
Question 2 of 5
Natural killer cells
Correct Answer: B
Rationale: NK cells lyse virally infected cells and tumor cells as part of innate immunity, without antigen presentation.
Question 3 of 5
What stage of an adaptive immune response involves secretion of antibody from a large plasma cell with extensive endoplasmic reticulum?
Correct Answer: C
Rationale: The effector phase includes antibody secretion by plasma cells, which have extensive ER for protein production.
Question 4 of 5
The genes encoding which of the following can undergo hypermutation to create receptors that are an even better fit for foreign antigens?
Correct Answer: A
Rationale: BCRs undergo somatic hypermutation in B cells to enhance antigen affinity, unlike TCRs or MHCs.
Question 5 of 5
Which of the following is NOT true regarding effective immunogens?
Correct Answer: D
Rationale: Effective immunogens (e.g., proteins) don't require carriers; this is true for haptens, not standalone immunogens.