ATI RN
ATI Pharmacology Study Guide Questions
Question 1 of 4
Which of the following is a first-line medication for generalized tonic-clonic seizures?
Correct Answer: D
Rationale: Topiramate, a broad-spectrum antiepileptic, treats generalized tonic-clonic seizures by blocking sodium channels, enhancing GABA, and inhibiting glutamate, making it a first-line option per guidelines. Ethosuximide targets absence seizures. Felbamate, vigabatrin, and ezogabine have narrower uses or toxicity risks (e.g., aplastic anemia, vision loss), limiting them to refractory cases. Topiramate's efficacy, tolerability, and broad action suit primary generalized seizures, distinguishing it as a standard choice.
Question 2 of 4
A client calls the nurse help-line and says, 'My friend and I have been swimming and drinking beer all day and he took a couple of swigs of Robitussin DM (dextromethorphan) about 15 minutes ago. Now he is acting funny and seeing things.' What should the nurse consider when formulating a response?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 4
A client with hyperlipidemia is prescribed simvastatin (Zocor). Which instruction should the nurse include?
Correct Answer: A
Rationale: Simvastatin, a statin, lowers cholesterol by inhibiting HMG-CoA reductase, most active at night when synthesis peaks. Evening dosing optimizes efficacy. Grapefruit juice increases levels, risking toxicity. Stopping if normal risks rebound. Breakfast misses the cycle. Evening aligns with simvastatin's pharmacodynamics, key in hyperlipidemia where timing boosts results, making A the key instruction.
Question 4 of 4
The systemic bioavailability of the following oral drugs is increased if taken in the fasting state:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.