Which of the following is a common use for diuretics?

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Question 1 of 5

Which of the following is a common use for diuretics?

Correct Answer: B

Rationale: Diuretics are commonly used to reduce fluid retention in conditions like heart failure by increasing urine output. This helps decrease edema and reduce the workload on the heart. Other choices are incorrect: A is treated with lipid-lowering medications, C with sleep aids, and D with antidiabetic drugs.

Question 2 of 5

A patient with chronic obstructive pulmonary disease (COPD) is prescribed ipratropium. Ipratropium works by:

Correct Answer: C

Rationale: The correct answer is C: Blocking muscarinic receptors in the airways. Ipratropium is an anticholinergic medication that works by blocking muscarinic receptors, leading to bronchodilation in patients with COPD. This mechanism of action reduces bronchoconstriction and improves airflow. A: Relaxing bronchial smooth muscle by stimulating beta-2 adrenergic receptors is incorrect because ipratropium does not act on beta-2 adrenergic receptors. B: Inhibiting the enzyme that breaks down acetylcholine in the lungs is incorrect as ipratropium does not affect the breakdown of acetylcholine. D: Inhibiting the release of histamine from mast cells is incorrect because ipratropium does not target histamine release. In summary, the correct answer is C because ipratropium's mechanism of action involves blocking muscarinic receptors to achieve bronchodilation in COPD patients

Question 3 of 5

A 70-year-old patient with hypertension is prescribed clonidine. Clonidine works by:

Correct Answer: A

Rationale: The correct answer is A: Inhibiting the release of norepinephrine in the brainstem. Clonidine is a centrally acting alpha-2 adrenergic agonist that works by inhibiting norepinephrine release in the brainstem, leading to decreased sympathetic outflow and ultimately reducing blood pressure. Choices B, C, and D are incorrect because clonidine does not act by blocking beta-adrenergic receptors in the heart, promoting vasodilation by inhibiting calcium channels, or increasing the excretion of sodium and water in the kidneys. The primary mechanism of clonidine's antihypertensive effect lies in its action on norepinephrine release in the brainstem.

Question 4 of 5

A patient with asthma is prescribed fluticasone. Fluticasone is classified as:

Correct Answer: B

Rationale: The correct answer is B: A corticosteroid. Fluticasone is a corticosteroid that works by reducing inflammation in the airways, which is crucial in managing asthma. Corticosteroids are the mainstay of asthma treatment as they help to decrease airway inflammation and prevent asthma symptoms. Choice A, a beta-agonist, is incorrect because beta-agonists work by relaxing the muscles around the airways and are usually used as rescue inhalers for quick relief of asthma symptoms. Choice C, a leukotriene modifier, is incorrect as leukotriene modifiers work by blocking the action of certain immune system chemicals that cause asthma symptoms, but they are not the classification for fluticasone. Choice D, an anticholinergic agent, is incorrect as anticholinergics work by blocking acetylcholine, a neurotransmitter that causes airway constriction, and are typically used in conditions like COPD, not as the

Question 5 of 5

This graph illustrates the dose-response relationship for the effect of the beta agonist isoproterenol on an isolated perfused heart, both alone and in the presence of different fixed concentrations of Drug X. Based upon the data shown, Drug X is most likely a(n):

Correct Answer: B

Rationale: The correct answer is B: Competitive antagonist. This can be determined by observing that the presence of Drug X shifts the dose-response curve for isoproterenol to the right without affecting the maximal response. This indicates competitive antagonism, where Drug X competes with isoproterenol for the same receptor site without affecting the efficacy of isoproterenol. Choice A (Beta agonist) is incorrect because the graph does not show any direct agonistic effect of Drug X. Choice C (Irreversible antagonist) is incorrect because the effect of Drug X is reversible, as shown by the ability of isoproterenol to still elicit a response in the presence of Drug X. Choice D (Noncompetitive antagonist) is incorrect because noncompetitive antagonists typically reduce the maximal response of the agonist, which is not seen in this graph.

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