ATI RN
Pediatric Genetic Disorders Questions
Question 1 of 5
which of the following human genetic disorders is sex linked?
Correct Answer: A
Rationale: Hemophilia is X-linked recessive, unlike PKU, cystic fibrosis (autosomal recessive), and achondroplasia (autosomal dominant).
Question 2 of 5
Cancer cells are not:
Correct Answer: A
Rationale: Cancer cells lose contact inhibition (normal cells stop dividing when touching), enabling uncontrolled growth.
Question 3 of 5
Genes that normally prevent cell division are:
Correct Answer: A
Rationale: Tumor suppressor genes (e.g., RB, p53) inhibit cell division to prevent cancer.
Question 4 of 5
The first step in FAP colon cancer usually involves mutation of the gene:
Correct Answer: A
Rationale: APC mutation is the initial event in FAP, leading to adenoma formation.
Question 5 of 5
The BRAC1 gene is involved in regulating:
Correct Answer: C
Rationale: BRCA1 (likely meant here) is a tumor suppressor involved in DNA repair, particularly double-strand breaks.