Which of the following have not provided examples of secondary immunodeficiency?

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Pediatric Immunization NCLEX Questions Quizlet Questions

Question 1 of 5

Which of the following have not provided examples of secondary immunodeficiency?

Correct Answer: D

Rationale: High fat diet is not a well-documented cause of secondary immunodeficiency, unlike viral infections (e.g., HIV), lymphoproliferative disorders, or cytotoxic drugs.

Question 2 of 5

An article published in the Oncoimmunology journal in September 2018. It is discussing an immunotherapy approach that relies on designing and infecting the cancer patient two viruses expressing Melanoma-associated antigen A3 (MAGE-A3). The two viruses, a replication-deficient type-5 human adenoviral (Ad-MAGEA3) and Maraba MGI rhabdovirus(MGI-MAGEA3), are studied in this article preclinically by infecting nonhuman primates(monkeys). This immunotherapy approach is considered:

Correct Answer: A

Rationale: Using viruses to express tumor antigens like MAGE-A3 to stimulate an immune response classifies this as a vaccination strategy in cancer immunotherapy.

Question 3 of 5

Matching: Complement deficiency - Nonpitting edema

Correct Answer: D

Rationale: C1 inhibitor deficiency causes hereditary angioedema, characterized by nonpitting edema due to unregulated bradykinin production. Other complement deficiencies do not typically present with this feature.

Question 4 of 5

Matching: Immunodeficiency - Elevated IgE levels and eosinophilia

Correct Answer: D

Rationale: Hyper-IgE syndrome is defined by elevated IgE and eosinophilia, alongside recurrent infections and skin findings.

Question 5 of 5

In addition to recurrent staphylococcal abscesses and elevated serum IgE, the clinical manifestations of hyperimmunoglobulinemia E (hyper-IgE) syndrome frequently include which of the following?

Correct Answer: B

Rationale: Hyper-IgE syndrome commonly includes pneumatoceles (lung cysts) from recurrent pneumonias, alongside staphylococcal abscesses and high IgE.

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