Which of the following features do MAO inhibitors and tricyclic antidepressants have in common?

Correct Answer: C

Rationale: Rationale: C: Both MAO inhibitors and tricyclic antidepressants increase levels of biogenic amines like serotonin, norepinephrine, and dopamine by inhibiting their reuptake or breakdown. A: Both act presynaptically by inhibiting the reuptake of neurotransmitters, not postsynaptically. B: Only MAO inhibitors interact with certain foods to cause hypertensive crisis, not tricyclic antidepressants. D: Tricyclic antidepressants are used for bipolar depression, not the manic phase.

Correct Answer: D

Rationale: Cocaine may cause powerful vasoconstrictive reactions, leading to myocardial infarctions due to increased blood pressure and heart strain. It can also result in multiple brain perfusion defects due to restricted blood flow. Additionally, cocaine use during pregnancy can lead to spontaneous abortion due to its harmful effects on fetal development. Therefore, the correct answer is D, as all of these adverse effects are associated with cocaine use. Choices A, B, and C are incorrect as they do not cover the full spectrum of potential harm caused by cocaine.

Correct Answer: B

Rationale: The correct answer is B: Isoprenaline. Isoprenaline is a non-selective beta2-adrenomimic because it stimulates both beta1 and beta2 adrenergic receptors. This leads to effects on both the heart and lungs. Salbutamol, Salmeterol, and Terbutaline are selective beta2-adrenomimics, meaning they primarily target beta2 receptors in the lungs, resulting in bronchodilation without significant effects on the heart. Therefore, they do not belong to the category of non-selective beta2-adrenomimics like Isoprenaline.

Correct Answer: A

Rationale: The correct answer is A: TRUE. Iron deficiency anemia leads to symptoms like pallor, fatigue, dizziness, exertional dyspnea due to decreased oxygen-carrying capacity in the blood. Iron is essential for hemoglobin production, which carries oxygen to tissues. Other choices are incorrect: B is false because iron deficiency anemia does lead to these symptoms. C is incorrect because not all symptoms listed are present in every case of iron deficiency anemia. D is incorrect because the symptoms mentioned are associated with iron deficiency anemia.

Correct Answer: C

Rationale: Rationale: 1. Dobutamine is a beta-1 adrenergic receptor agonist used as an inotropic drug. 2. Continuous use of dobutamine leads to receptor desensitization, causing tolerance. 3. Tolerance develops within a few days due to downregulation of beta-1 receptors. 4. Amrinone and amiodarone are not inotropic drugs and do not cause tolerance. 5. Adenosine is not an inotropic drug and has a rapid onset and short duration of action.