ATI RN
Basic Principles of Pharmacology Quizlet Questions
Question 1 of 5
Which of the following features best explains why formulation W produces the largest plasma concentration-time curve of the drug?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
What percentage of the administered drug will be eliminated by the liver?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following drugs has the largest volume of distribution?
Correct Answer: C
Rationale: The volume of distribution (Vd) is a pharmacokinetic parameter that indicates the extent of a drug's distribution in the body. The drug with the largest Vd will have the most extensive distribution. In this case, Drug R has the largest Vd of 100 L, indicating that it has the largest volume of distribution among the options provided.
Question 4 of 5
Which of the curves best depicts the log dose-response curve of that agonist when a xed dose of a competitive α antagonist is given concomitantly?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
What term best defines the cimetidine-diazepam interaction where the sedative effect of diazepam increased significantly?
Correct Answer: B
Rationale: The cimetidine-diazepam interaction, where the sedative effect of diazepam increased significantly due to the inhibition of the cytochrome P-450 system by cimetidine, can be best defined as potentiation. Potentiation refers to the enhancement of one drug's effect by another, leading to a greater overall effect than either drug alone. In this case, cimetidine potentiates the sedative effect of diazepam by inhibiting its metabolism, resulting in increased sedation.