ATI RN
Basic Principles of Pharmacology Quizlet Questions
Question 1 of 5
Which of the following factors regulates the relationship between drug concentration and drug-receptor complex formation?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
A new drug was tested in an in vitro system. It was found that only one enantiomer of the racemic pair bound substantially to a specific receptor, whereas the other enantiomer showed negligible binding. Which of the following terms best defines this property?
Correct Answer: A
Rationale: Stereoselectivity refers to the phenomenon where one enantiomer of a racemic pair exhibits a significantly different interaction compared to the other enantiomer. In this case, the enantiomer that binds substantially to the receptor while the other does not demonstrates stereoselectivity. The term "intrinsic activity" refers to the ability of a drug to activate a receptor, "affinity" refers to the strength of binding between a drug and its receptor, and "potency" refers to the concentration of a drug required to produce a specific effect. Therefore, the correct answer is A.
Question 3 of 5
What was most likely the immediate consequence of the activation of beta receptors in the 9-year-old boy suffering from mild asthma?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Consumer safety became an important issue during the latter part of the twentieth century because of the
Correct Answer: D
Rationale: a and c' is correct because consumer safety rose in prominence due to increased drug use (a) and more over-the-counter (OTC) medications (c), heightening risks of misuse and adverse effects. 'b' (therapeutic properties) is a constant concern, not unique to the late twentieth century. Choosing 'a' or 'c' alone ignores the combined impact, and 'all of the above' overstates 'b's specificity. Late twentieth-century trends, like OTC expansion and drug culture shifts, drove safety focus, per historical pharmacology context.
Question 5 of 5
The concentration of active ingredients in a drug preparation
Correct Answer: A
Rationale: Potency' is correct because it defines the concentration or strength of active ingredients needed for a therapeutic effect. 'Quality' is about overall standards, not concentration specifically. 'Efficacy' is the ability to produce results, not ingredient level. 'Purity' is absence of contaminants, not concentration. Potency directly relates to dosage and effect strength, a key pharmacology concept distinguishing it from the others.