ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Which of the following effects most likely occurred during surgery?
Correct Answer: D
Rationale: The correct answer is D. Increased skeletal muscle tone, fever, skeletal muscle contractions, and diaphoresis are signs of malignant hyperthermia, a rare but life-threatening condition triggered by certain anesthesia agents like halothane and succinylcholine in susceptible individuals. This condition can lead to severe metabolic and respiratory acidosis, cardiac arrhythmias, and hyperkalemia.
Question 2 of 5
When used as monotherapy, a major toxicity of gemfibrozil is increased risk of
Correct Answer: B
Rationale: Gemfibrozil increases cholesterol excretion in bile, which can lead to gallstone formation (cholelithiasis).
Question 3 of 5
Trichloroethanol is the active metabolite of:
Correct Answer: D
Rationale: Chloral hydrate (choice D) is metabolized to trichloroethanol, which depresses the CNS, inducing sedation. Morphine (choice A) metabolizes to active compounds like morphine-6-glucuronide, not trichloroethanol. Clorazepate (choice B) becomes desmethyldiazepam, a benzodiazepine. Phenobarbitone (choice C) is a barbiturate, not metabolized to trichloroethanol. This identifies Chloral hydrate's metabolic pathway, key for its hypnotic use.
Question 4 of 5
The consumption of shellfish harvested during a red tide (due to a large population of a dinoflagellate species) is not recommended. This is because the shellfish are likely to contain
Correct Answer: D
Rationale: Saxitoxin, produced by dinoflagellates, causes paralytic shellfish poisoning by blocking sodium channels.
Question 5 of 5
Which of the following is the most trouble-shooter in spinal anaesthesia?
Correct Answer: A
Rationale: Sympathetic block can be the most troublesome in spinal anaesthesia leading to hypotension and other complications.