Which of the following drugs would be contraindicated for a patient undergoing major surgery to remove a breast carcinoma who has chronic obstructive pulmonary disease and is a heavy smoker?

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

Which of the following drugs would be contraindicated for a patient undergoing major surgery to remove a breast carcinoma who has chronic obstructive pulmonary disease and is a heavy smoker?

Correct Answer: A

Rationale: Tubocurarine is a non-depolarizing muscle relaxant that can cause histamine release, leading to bronchoconstriction. In a patient with chronic obstructive pulmonary disease and a history of smoking, using tubocurarine could exacerbate respiratory issues, making it contraindicated in this case.

Question 2 of 5

Which of the following opioid analgesics has very low protein binding?

Correct Answer: A

Rationale: Morphine has very low protein binding compared to other opioids allowing it to have more free drug available in circulation.

Question 3 of 5

Compared with other antidepressant drugs, mirtazapine has the distinctive ability to act as an antagonist of

Correct Answer: A

Rationale: Mirtazapine enhances norepinephrine and serotonin release by blocking presynaptic alpha2 receptors.

Question 4 of 5

Which of the following best describes the MAC of an inhalational anesthetic?

Correct Answer: A

Rationale: The MAC (minimum alveolar concentration) of an inhalational anesthetic is defined as the alveolar concentration at which 50% of patients do not move in response to a surgical stimulus. It is related to the blood/gas partition coefficient of the anesthetic, which determines the rate at which the anesthetic enters and leaves the bloodstream, influencing its potency.

Question 5 of 5

Acute opium poisoning is treated by intravenous administration of

Correct Answer: A

Rationale: Naloxone is an opioid antagonist that rapidly reverses respiratory depression in opioid overdose.

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