Which of the following drugs would be contraindicated for a patient undergoing major surgery to remove a breast carcinoma who has chronic obstructive pulmonary disease and is a heavy smoker?

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

Which of the following drugs would be contraindicated for a patient undergoing major surgery to remove a breast carcinoma who has chronic obstructive pulmonary disease and is a heavy smoker?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

Which of the following drugs was most likely prescribed for the 45-year-old man recently diagnosed with partial seizures?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Which of the following drugs would be most appropriate for this patient to substitute for valproic acid therapy?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Which of the following drugs was most likely prescribed for the 12-year-old girl with refractory absence seizures?

Correct Answer: B

Rationale: In this case, the neurologist decided to add a second-generation antiepileptic drug that blocks voltage-gated Na+ and Ca2+ channels and may inhibit the synaptic release of glutamate. Among the choices, Lamotrigine fits this description as it is known to block voltage-gated sodium channels, making it the most likely drug prescribed for the patient.

Question 5 of 5

Which of the following drugs was most likely prescribed for the 44-year-old woman with poorly controlled simple partial seizures that was only partially effective with valproic acid therapy?

Correct Answer: D

Rationale: The recently approved drug that acts with a novel mechanism of action, a noncompetitive blockade of AMPA receptors on brain neurons, is Perampanel. Given that the patient had poorly controlled seizures with valproic acid, adding Perampanel would provide a different mechanism of action to improve seizure control.

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