ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Which of the following drugs would be contraindicated for this patient with cogwheel rigidity and decreased dopamine metabolism in the striatum?
Correct Answer: B
Rationale: Carbidopa is a drug that inhibits the peripheral metabolism of levodopa, allowing more levodopa to reach the brain and be converted to dopamine. In this patient with decreased dopamine metabolism in the striatum, adding carbidopa to the regimen would further enhance the availability of levodopa in the brain, thereby improving symptoms of parkinsonism. The other options do not directly address the issue of decreased dopamine metabolism in the striatum.
Question 2 of 5
A 21-year-old male has recently begun pimozide therapy for Tourette's disorder. His parents bring him to the emergency department. They describe that he has been having “different appearing tics†than before, such as prolonged contraction of the facial muscles. While being examined, he experiences opsichotomus (type of extrapyramidal spasm of the body in which the head and heels are bent backward and the body is bowed forward). Which of the following drugs would be beneficial in reducing these symptoms?
Correct Answer: A
Rationale: Benztropine, an anticholinergic agent, is used to treat extrapyramidal symptoms like dystonia caused by antipsychotic medications.
Question 3 of 5
Following agent is generally used in allergic rhinitis
Correct Answer: D
Rationale: All of these are corticosteroids commonly used for allergic rhinitis due to their anti-inflammatory effects.
Question 4 of 5
Which of the following drugs would be contraindicated for this patient with cogwheel rigidity and decreased dopamine metabolism in the striatum?
Correct Answer: B
Rationale: Carbidopa is a drug that inhibits the peripheral metabolism of levodopa, allowing more levodopa to reach the brain and be converted to dopamine. In this patient with decreased dopamine metabolism in the striatum, adding carbidopa to the regimen would further enhance the availability of levodopa in the brain, thereby improving symptoms of parkinsonism. The other options do not directly address the issue of decreased dopamine metabolism in the striatum.
Question 5 of 5
A 73-year-old man presents to his primary care physician complaining of a weak stream and nocturia four times at night. He is very sensitive to the medication side effects and is reluctant to take medications for this reason. Physical examination reveals a mildly enlarged prostate. Treatment of this condition may involve the use of which of the following agents to minimize side effects?
Correct Answer: D
Rationale: Tamsulosin is an α1-adrenergic receptor antagonist that is selective for the prostate and bladder neck, minimizing systemic side effects like hypotension.