Which of the following drugs was most likely administered in the detoxification program?

Correct Answer: D

Rationale: Meperidine is a commonly used opioid analgesic that is often used in detoxification programs due to its ability to help manage withdrawal symptoms. In this case, the patient was undergoing a detoxification program supervised by surgery, and a drug was administered intravenously. Meperidine is a likely choice as it can help alleviate withdrawal symptoms and manage pain during the detoxification process.

Correct Answer: D

Rationale: The patient's signs and symptoms, such as mydriasis, tonic-clonic seizure, shallow respiration, and cardiovascular collapse leading to death, are consistent with LSD intoxication. LSD is known to cause agitation, altered mental status, and severe physiological effects, making it the most likely cause of the patient's death.

Correct Answer: D

Rationale: The signs and symptoms described in the text, such as talkativeness, mydriasis, muscle twitching, hand tremor, elevated blood pressure, and increased heart rate, are consistent with the effects of amphetamine use. Amphetamine is a stimulant drug that can cause these symptoms by increasing the release of neurotransmitters like dopamine and norepinephrine in the brain. Additionally, the patient being a drug user who tried different drugs supports the likelihood of amphetamine use, as it is commonly abused for its stimulant effects.

Correct Answer: D

Rationale: In this question regarding agents that often cause vasoconstriction, the correct answer is option D) PGF2α. Prostaglandin F2α (PGF2α) is known for its vasodilatory effects, not vasoconstriction. Angiotensin II (option A) is a potent vasoconstrictor that plays a critical role in regulating blood pressure by constricting blood vessels. Methysergide (option B) is a vasoconstrictor used in the treatment of migraines and cluster headaches. Prostacyclin (option C) is a prostaglandin that causes vasodilation and inhibits platelet aggregation. Understanding the effects of different agents on vascular tone is crucial in the context of pharmacology and patient care. Nurses and healthcare providers need to be knowledgeable about the actions of various drugs to anticipate and manage potential side effects and complications. This knowledge is especially important when caring for patients with cardiovascular conditions or those receiving vasoactive medications.

Correct Answer: B

Rationale: The correct answer is B) Colchicine. Colchicine is not useful in dysmenorrhea because it is primarily used to treat gout by reducing inflammation caused by uric acid crystals in the joints. A) Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that helps relieve pain and reduce inflammation, making it useful in dysmenorrhea. C) Ibuprofen is also an NSAID that helps reduce pain and inflammation, commonly used to alleviate dysmenorrhea symptoms. D) Rofecoxib is a selective COX-2 inhibitor, another type of NSAID that can be effective in managing pain associated with dysmenorrhea. Educationally, understanding the mechanisms of action of different drugs is crucial for nursing practice. Knowing which drugs are appropriate for specific conditions like dysmenorrhea ensures safe and effective patient care. It is important for nurses to be able to differentiate between various drug classes and their indications to make informed clinical decisions.