ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Questions Quizlet Questions
Question 1 of 5
Which of the following drugs was most likely administered for muscle relaxation in the 74-year-old man with impaired hepatic and renal function undergoing abdominal surgery?
Correct Answer: C
Rationale: In a patient with impaired hepatic and renal function, Vecuronium is the most appropriate choice for muscle relaxation as it is primarily eliminated through hepatic metabolism and does not require renal excretion. Succinylcholine is contraindicated in patients with impaired renal function due to the risk of hyperkalemia. Tubocurarine, Mivacurium, and Cisatracurium may have prolonged effects in patients with impaired liver function, making Vecuronium the safest choice in this scenario.
Question 2 of 5
Which of the following muscle relaxants would be contraindicated in a patient with a deficiency of plasma cholinesterase?
Correct Answer: A
Rationale: Tubocurarine is a non-depolarizing muscle relaxant that is metabolized by plasma cholinesterase. In a patient with a deficiency of plasma cholinesterase, tubocurarine would not be metabolized properly, leading to prolonged effects and potential toxicity. Therefore, it would be contraindicated in this patient.
Question 3 of 5
Which of the following muscle relaxants was most likely given to a patient who exhibited transient muscle fasciculations followed by generalized paralysis within 1 minute of administration?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A 34-year-old woman suffering from hemifacial spasms started treatment with botulinum toxin injected directly into the abnormally contracting muscles. Which of the following molecular actions most likely mediated the therapeutic effect of the drug in the patient's disorder?
Correct Answer: D
Rationale: The correct answer is D. Botulinum toxin works by inhibiting the release of acetylcholine from cholinergic terminals, leading to muscle paralysis and relaxation. This action prevents the excessive muscle contractions seen in hemifacial spasms. Inhibition of acetylcholine exocytosis from cholinergic terminals is the mechanism behind the therapeutic effect of botulinum toxin in this case.
Question 5 of 5
Which of the following drugs would be most appropriate for this patient?
Correct Answer: B
Rationale: Baclofen is a muscle relaxant commonly used to treat muscle spasms, making it the most appropriate choice for a patient with muscle spasms. Phenobarbital is an antiseizure medication and would not be indicated for this patient. Tubocurarine and succinylcholine are neuromuscular blocking agents used during surgery, but baclofen would be more appropriate for muscle spasms outside of surgical settings. Chlorpromazine is an antipsychotic medication and would not be indicated for muscle spasms.