Which of the following drugs valuable in the treatment of edema and metabolic alkalosis?

Correct Answer: D

Rationale: The correct answer is D: Acetazolamide. Acetazolamide is a carbonic anhydrase inhibitor that helps in the treatment of edema and metabolic alkalosis by promoting diuresis and increasing renal excretion of bicarbonate. It is effective in treating conditions associated with fluid retention and alkalosis. A: Digoxin is a cardiac glycoside used to treat heart conditions like heart failure and atrial fibrillation, not edema or metabolic alkalosis. B: Spironolactone is a potassium-sparing diuretic commonly used for conditions like hypertension and heart failure, but not specifically for metabolic alkalosis. C: Dobutamine is a beta-adrenergic agonist used in acute heart failure or shock situations, not for edema or alkalosis. In summary, Acetazolamide is the correct choice as it directly targets edema and metabolic alkalosis by affecting renal excretion of bicarbonate. Other options are

Correct Answer: B

Rationale: The correct answer is B: Thiazides. Thiazides work by inhibiting the Na+/Cl- transporter in the distal convoluted tubule, leading to decreased sodium reabsorption and increased urine output. This results in decreased blood volume and lower blood pressure. Spironolactone (A) works by blocking aldosterone receptors, affecting potassium and sodium balance. Furosemide (C) and Ethacrynic acid (D) act on the loop of Henle, inhibiting the Na+/K+/2Cl- transporter. Therefore, the correct answer is B because thiazides specifically target the Na+/Cl- transporter in the distal convoluted tubule.

Correct Answer: B

Rationale: The correct answer is B: By lightly striking the fist at the costovertebral angle. This method is known as percussion and is used to assess for kidney tenderness or pain. Percussion helps to identify any abnormalities in the kidneys or surrounding structures. Auscultation (choice A) is used to listen for sounds, not assess for tenderness. Observing for signs of bleeding (choice C) and monitoring pressure dressing (choice D) are not appropriate methods for assessing kidney tenderness or pain.

Correct Answer: B

Rationale: The correct answer is B: Help flush the stones through the urinary tract. Increasing fluid intake can help dilute the urine, preventing stone formation and aiding in the passage of existing stones. Adequate hydration promotes frequent urination, which can help flush out the stones and reduce the risk of complications. Choices A, C, and D are incorrect. A: Concentrating the urine can actually exacerbate stone formation. C: Struvite crystals are not typically formed in nephrolithiasis. D: Breaking down stones requires medical intervention, not just increased fluid intake.

Correct Answer: C

Rationale: The correct answer is C because a history of intermittent catheterization increases the risk of urinary tract infections due to potential introduction of bacteria into the urinary system. This directly supports the diagnosis of a urinary tract infection. A: The wife's history is irrelevant unless the patient had direct contact or shared personal items with her. B: Prostate disease does not directly correlate with a urinary tract infection. D: Kidney stones are not directly related to urinary tract infections unless there was an associated infection during the stone removal.