Which of the following drugs most likely produced the greatest increase in diuresis in the subject?

Correct Answer: D

Rationale: The correct answer is D (Drug S) because it is a loop diuretic, which acts on the ascending loop of Henle to inhibit sodium and chloride reabsorption, leading to a significant increase in diuresis. Loop diuretics are the most potent diuretics among the options provided. Drug P (Choice A) is a thiazide diuretic that acts on the distal convoluted tubule and is less potent than loop diuretics. Drug Q (Choice B) is a potassium-sparing diuretic that acts on the collecting ducts and is weaker in terms of diuretic effect compared to loop diuretics. Drug R (Choice C) is an aldosterone antagonist that acts on the distal tubules and collecting ducts, but it is less potent compared to loop diuretics in increasing diuresis.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.