ATI RN
Principles of Pharmacology Quizlet Questions
Question 1 of 5
Which of the following drugs most likely has the highest oral bioavailability based on the given data?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
What is the main site of distribution for infliximab?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following was most likely the half-life of the drug (in hours)?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following terms best defines the tested drug?
Correct Answer: A
Rationale: The tested drug is best defined as a noncompetitive antagonist, which binds irreversibly to the receptor site and prevents the activation of the receptor by the endogenous ligand. This property distinguishes noncompetitive antagonists from other types of drugs and is important in understanding their mechanism of action and therapeutic effects.
Question 5 of 5
What factors regulate the relationship between the concentration of a drug and the association and dissociation of the drug-receptor complex?
Correct Answer: D
Rationale: The law of mass action governs the relationship between the concentration of a drug and the association and dissociation of the drug-receptor complex. According to this law, the rate of a chemical reaction is directly proportional to the product of the concentrations of the reacting substances. In the context of pharmacology, this means that the concentration of a drug influences its interaction with receptors, affecting the pharmacological response.