ATI RN
Peripheral Nervous System Drugs Questions
Question 1 of 5
Which of the following drugs most likely caused the patient's nausea?
Correct Answer: D
Rationale: The correct answer is D: Omeprazole. Omeprazole is a proton pump inhibitor used to reduce stomach acid production, which can cause nausea as a side effect. Carbidopa is used to treat Parkinson's disease, Benztropine is an anticholinergic used to treat Parkinson's symptoms, and Pramipexole is a dopamine agonist also used in Parkinson's disease. None of these drugs are known to commonly cause nausea as a side effect.
Question 2 of 5
Which of the following drugs most likely caused the patient's symptoms of abnormal growth of the breast?
Correct Answer: B
Rationale: The correct answer is B: Risperidone. Risperidone is an atypical antipsychotic known to cause side effects such as abnormal breast growth (gynecomastia) due to its effects on hormone levels. Haloperidol (A) is a typical antipsychotic with a lower likelihood of causing gynecomastia. Amitriptyline (C) is a tricyclic antidepressant that does not typically cause gynecomastia. Buspirone (D) is an anxiolytic medication that is not associated with gynecomastia. Therefore, based on the patient's symptoms, the most likely culprit is Risperidone due to its known side effect profile.
Question 3 of 5
A drug with which of the following molecular mechanisms of action would be appropriate for this patient?
Correct Answer: C
Rationale: The correct answer is C: Inhibition of serotonin transporter. This mechanism of action would be appropriate for this patient as it increases serotonin levels in the synaptic cleft, which can help alleviate symptoms of depression. Monoamine oxidase A inhibition (Choice A) is used for atypical depression. Serotonergic receptor blockade (Choice B) can worsen depression symptoms. Blockade of β receptors (Choice D) is used for conditions like hypertension, not depression. In summary, choice C is the most suitable for treating depression by increasing serotonin levels, while the other choices are either ineffective or potentially harmful for this condition.
Question 4 of 5
Which of the following drugs most likely caused the symptom reported by the patient?
Correct Answer: D
Rationale: The correct answer is D: Chlorpromazine. The patient reported symptoms are likely extrapyramidal side effects, such as tremors, muscle rigidity, and akathisia, which are common with typical antipsychotics like chlorpromazine. Lithium (A) is used for bipolar disorder, not associated with these side effects. Amitriptyline (B) is a tricyclic antidepressant, known for sedation and anticholinergic effects. Fluoxetine (C) is a selective serotonin reuptake inhibitor, not known for causing extrapyramidal symptoms. Therefore, based on the symptoms described, chlorpromazine is the most likely culprit.
Question 5 of 5
Which of the following drugs most likely interacted with metoclopramide, thus triggering the adverse effects reported by the patient?
Correct Answer: A
Rationale: The correct answer is A: Amitriptyline. Metoclopramide interacts with amitriptyline by inhibiting its metabolism, leading to increased levels of amitriptyline in the body. This can result in adverse effects such as sedation, confusion, and potential serotonin syndrome. Explanation: 1. Metoclopramide is known to inhibit CYP2D6 enzyme, which is responsible for metabolizing amitriptyline. 2. Increased amitriptyline levels can lead to enhanced sedative effects and central nervous system depression. 3. The combination can also increase the risk of serotonin syndrome due to the additive serotonergic effects of both drugs. Summary: B: Lithium - Lithium does not have a significant metabolic interaction with metoclopramide. C: Zolpidem - Zolpidem is primarily metabolized by different enzymes and does not interact significantly with metoclopramide. D: Paroxetine - Although both