Which of the following drugs is proteolytic enzyme?

Correct Answer: B

Rationale: The correct answer is B: Desoxiribonuclease. Desoxiribonuclease is a proteolytic enzyme that breaks down DNA molecules. Proteolytic enzymes are enzymes that break down proteins into smaller peptides or amino acids. Potassium iodide, Carbocysteine, and Acetylcysteine are not proteolytic enzymes, they are used for different purposes such as treating respiratory conditions or as expectorants. Therefore, B is the correct answer as it is the only option that is a proteolytic enzyme.

Correct Answer: B

Rationale: Step-by-step rationale: 1. Digibind (Digoxin immune fab) is the best choice in severe digitalis intoxication as it binds to digoxin, reducing its effects. 2. Lidocaine is used for cardiac arrhythmias but not specific to digoxin toxicity. 3. Oral potassium supplementation can worsen digoxin toxicity by increasing intracellular potassium. 4. Reducing the dose of the drug is not effective in severe intoxication. Summary: - Digibind is specific for digoxin toxicity by binding to the drug. - Lidocaine, oral potassium, and reducing the drug dose are not effective in severe digitalis intoxication.

Correct Answer: D

Rationale: The correct answer is D, "All of the above." Calcium channel blockers are commonly used for angina pectoris, hypertension, and supraventricular tachyarrhythmias. They work by blocking the entry of calcium into the cells, leading to vasodilation, decreased myocardial contractility, and reduced heart rate. This helps in managing angina by reducing oxygen demand, controlling blood pressure, and treating certain types of arrhythmias. Therefore, the main clinical use of calcium channel blockers encompasses all three conditions mentioned in the choices.

Correct Answer: C

Rationale: The correct answer is C: Beta-1 adrenoreceptors (leads to enhanced cardiac output). Dopamine at medium doses mainly influences the Beta-1 adrenoreceptors in the heart, leading to increased heart rate and contractility, thus enhancing cardiac output. This is because dopamine acts as a positive inotropic and chronotropic agent on the heart. Choices A and B are incorrect because dopamine does not primarily act on Alfa-adrenoreceptors (A) causing peripheral vasoconstriction or dopamine receptors (B) causing vasodilation of renal and mesenteric vessels at medium doses. Choice D is incorrect because dopamine at medium doses primarily influences Beta-1 adrenoreceptors, not all the options listed.

Correct Answer: A

Rationale: The correct answer is A: Iodide 1 part in 100000. In an area where goitre is endemic, iodide is used to treat iodine deficiency, which is a common cause of goitre. Iodide supplementation helps in restoring normal thyroid function by providing the necessary iodine for thyroid hormone synthesis. Propylthiouracil and Methimazole are used to treat hyperthyroidism, not goitre. Therefore, they are incorrect choices. Option D is incorrect because not all the choices can be used interchangeably for treating goitre.