Which of the following drugs is more active when applied topically because it poorly passes cell membranes? (Thus used to treat severe eczema).

Correct Answer: D

Rationale: Budesonide is more effective when applied topically because it has poor cell membrane permeability, allowing it to remain localized at the site of application. This makes it particularly useful for treating severe eczema and other inflammatory skin conditions. Its localized action minimizes systemic side effects, making it a safer option for long-term topical use compared to other glucocorticoids.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.