ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 5
Which of the following drugs is contraindicated if there is a history of acute porphyria?
Correct Answer: C
Rationale: Acute porphyria involves heme synthesis defects, triggered by drugs inducing hepatic enzymes (e.g., CYP450). Quinine, used in malaria, isn't a major porphyria trigger. Atenolol, a beta-blocker, is porphyrin-safe, with minimal enzyme induction. Oral contraceptives, containing estrogens/progestins, induce ALA synthase, exacerbating acute porphyria, making them contraindicated. Heparin and amoxicillin don't significantly affect porphyrin metabolism. The contraceptive link reflects hormonal exacerbation of porphyric attacks, critical for safe prescribing in this rare condition.
Question 2 of 5
The primary function of luteinizing hormone (LH) in men is to
Correct Answer: D
Rationale: Luteinizing hormone (LH), from the pituitary, stimulates Leydig cells in the testes to produce testosterone, the primary male sex hormone, making its regulation LH's chief role in men. Sperm production is driven by follicle-stimulating hormone (FSH), not LH, though both support fertility. Secondary sex characteristics, like body hair, depend on testosterone, which LH indirectly influences by controlling its synthesis, not directly regulating the traits. Growth of male sex organs relies on androgens, again tied to testosterone, not LH's direct action. Testosterone regulation is LH's specific function, as it triggers the steroidogenesis pathway, critical for male physiology, distinguishing it from FSH's gamete focus and underscoring its hormonal primacy in this context.
Question 3 of 5
The nursing mother asks the nurse if it is all right to take St. John's wort for mild depression. What is the best response by the nurse?
Correct Answer: C
Rationale: St. John's wort, an herbal antidepressant, passes into breast milk, potentially affecting the baby-e.g., sedation or colic-making it unsafe without medical advice. Allergies lack evidence as a concern. Milk production isn't a known issue. Taste changes are unproven. Excretion risk is the primary concern, supported by pharmacokinetics, prioritizing infant safety.
Question 4 of 5
Which method would the nurse use to administer medications to school-age children?
Correct Answer: B
Rationale: School-age kids (6-12) grasp brief explanations-e.g., 'This helps your cough'-fitting their cognitive level, easing administration. Full decision-making exceeds maturity. Holding down distresses, not needed. Lengthy talks lose attention. Brief explanation leverages development, ensuring cooperation.
Question 5 of 5
The client receives hydroxychloroquine sulfate (Plaquenil). Which test does the nurse tell the client should be done on a regular basis?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.