Which of the following drugs is associated with the reaction of tendon dysfunction?

Correct Answer: D

Rationale: The correct answer is D: Fluoroquinolones. Fluoroquinolones are known to be associated with tendon dysfunction due to their potential to cause tendinitis and tendon rupture. This adverse effect is thought to be related to the drug's ability to disrupt collagen synthesis and structure in tendons. Digitalis (A) is used to treat heart conditions, niacin (B) for cholesterol, and tetracycline (C) for bacterial infections, none of which are linked to tendon dysfunction.

Correct Answer: C

Rationale: The correct answer is C: Antifungal. Drugs ending in the suffix (azole) are commonly used to treat fungal infections. The suffix indicates that the drug belongs to the azole class, which specifically targets fungal pathogens by inhibiting their growth. Therefore, a drug ending in (azole) is classified as an antifungal medication. Summary of other choices: A: H - Incorrect. There is no pharmacological relevance to the suffix (azole) in relation to the letter H. B: ACE inhibitor - Incorrect. Drugs ending in (pril) are commonly ACE inhibitors, not those ending in (azole). D: Beta agonist - Incorrect. Drugs ending in (ol) or (olol) are typically beta agonists, not those ending in (azole).

Correct Answer: D

Rationale: The correct answer is D: H antagonist. Drugs ending in the suffix (tidine) typically belong to the class of histamine H2-receptor antagonists. These drugs work by blocking the action of histamine on H2 receptors in the stomach, reducing the production of stomach acid. This is commonly used to treat conditions such as peptic ulcers and gastroesophageal reflux disease. Explanation of other choices: A: Antidepressant - Drugs ending in (pramine) or (ine) are more commonly associated with antidepressants. B: Protease inhibitor - Drugs ending in (navir) are typically protease inhibitors used in antiviral therapy. C: Beta antagonist - Drugs ending in (olol) are beta-blockers, which are used to treat conditions such as hypertension and heart disease, not related to (tidine) suffix.

Correct Answer: B

Rationale: The correct answer is B: Protease inhibitor. Drugs ending in the suffix (navir) are commonly used to inhibit protease enzymes in viruses, particularly in the treatment of HIV/AIDS. Protease inhibitors disrupt viral replication by preventing the cleavage of viral proteins, thus inhibiting the production of new infectious viral particles. Choice A, Antidepressant, is incorrect as drugs used to treat depression usually end in (ine) or (pram). Choice C, Beta antagonist, is incorrect as drugs affecting beta receptors typically end in (olol) or (lol). Choice D, H antagonist, is incorrect as drugs targeting histamine receptors usually end in (ine) or (idine).

Correct Answer: C

Rationale: The correct answer is C: Tetracycline. Tetracycline is associated with extreme photosensitivity due to its mechanism of action causing phototoxic reactions when exposed to sunlight. Digitalis (A) is a cardiac medication, niacin (B) is a B vitamin, and fluoroquinolones (D) are antibiotics, none of which are known to cause extreme photosensitivity reactions.