Which of the following drugs is associated with hepatitis as a reaction?

Correct Answer: C

Rationale: Correct Answer: C (Isoniazid) Rationale: 1. Isoniazid is known to cause drug-induced hepatitis due to its hepatotoxic effects. 2. It can lead to liver inflammation, causing hepatitis as a reaction. 3. Regular monitoring of liver function tests is essential when using isoniazid. Summary of other choices: A. Valproic acid: Can cause hepatotoxicity but not specifically linked to hepatitis. B. Quinidine: Mainly known for cardiac side effects, not commonly associated with hepatitis. D. Ethosuximide: Primarily used for treating absence seizures, not typically associated with hepatitis.

Correct Answer: B

Rationale: The correct answer is B: Diarrhea. Atropine, a cholinoreceptor blocker, inhibits acetylcholine, causing decreased GI motility leading to constipation. Atropine also increases pulse rate due to reduced vagal tone (A). It causes mydriasis by blocking cholinergic receptors in the eye (D). Diarrhea is not a typical side effect of atropine due to its anticholinergic properties.

Correct Answer: B

Rationale: The correct answer is B: ACE inhibitor. Drugs ending in the suffix (-pril) typically refer to ACE inhibitors, which are commonly used to treat hypertension and heart failure by inhibiting the angiotensin-converting enzyme. ACE inhibitors do not belong to the categories mentioned in the other choices. Choice A (H) is vague and does not provide any relevant information. Choice C (Antifungal) is incorrect as drugs ending in (-pril) are not typically used to treat fungal infections. Choice D (Beta agonist) is also incorrect as drugs ending in (-pril) do not belong to the class of beta agonists, which are used to treat conditions like asthma and COPD.

Correct Answer: B

Rationale: The correct answer is B: Hypotension. Prednisone toxicity typically causes hypertension, not hypotension. Prednisone can lead to increased blood pressure due to its sodium-retaining effects. Cataracts (A), Psychosis (C), and Acne (D) are all known side effects of Prednisone toxicity. Cataracts can form due to long-term steroid use, psychosis can occur especially at higher doses, and acne is a common skin side effect. Therefore, hypotension is the odd one out among the choices given.

Correct Answer: B

Rationale: Prednisone is a corticosteroid used to treat inflammatory conditions and certain types of cancer. Testicular cancer is not typically treated with Prednisone because it is a form of cancer that requires specific treatments such as surgery, chemotherapy, or radiation therapy. Prednisone is not the primary treatment option for testicular cancer. In contrast, Prednisone is commonly used to manage symptoms in conditions like Cushing's disease, lymphomas, and chronic leukemias by reducing inflammation and suppressing immune response. Therefore, choice B is the correct answer as Prednisone is not a standard treatment for testicular cancer.

Correct Answer: D

Rationale: Step 1: Ethosuximide is the correct answer as it is a known trigger for Stevens-Johnson syndrome due to its association with hypersensitivity reactions. Step 2: Valproic acid can cause liver toxicity but is not typically linked to Stevens-Johnson syndrome. Step 3: Quinidine is associated with drug-induced lupus but not commonly known to cause Stevens-Johnson syndrome. Step 4: Isoniazid is linked to drug-induced hepatitis but not typically associated with Stevens-Johnson syndrome. In summary, Ethosuximide is the correct choice due to its well-documented association with Stevens-Johnson syndrome, while the other options are linked to different adverse effects.

Correct Answer: D

Rationale: Explanation: Dexamethasone is a corticosteroid used to treat inflammation and conditions like asthma and Addison's disease, which involve inflammation or immune responses. Wilson's disease is a genetic disorder related to copper metabolism, not treated with Dexamethasone. Dexamethasone could worsen Wilson's disease due to its potential impact on copper levels.

Correct Answer: B

Rationale: The correct answer is B: Protease inhibitor. Drugs ending in the suffix (navir) are commonly used to inhibit protease enzymes in viruses, particularly in the treatment of HIV/AIDS. Protease inhibitors disrupt viral replication by preventing the cleavage of viral proteins, thus inhibiting the production of new infectious viral particles. Choice A, Antidepressant, is incorrect as drugs used to treat depression usually end in (ine) or (pram). Choice C, Beta antagonist, is incorrect as drugs affecting beta receptors typically end in (olol) or (lol). Choice D, H antagonist, is incorrect as drugs targeting histamine receptors usually end in (ine) or (idine).

Correct Answer: D

Rationale: The correct answer is D: Penicillamine. Penicillamine is a chelating agent that binds to copper and forms a complex that can be excreted from the body, making it an effective antidote for copper toxicity. Glucagon (A) is used for treating hypoglycemia, aminocaproic acid (B) is used to treat excessive bleeding, and atropine (C) is used to treat bradycardia and organophosphate poisoning, none of which are related to copper toxicity.