Which of the following drugs has both alfa1-selective and beta-blocking effects?

Correct Answer: A

Rationale: The correct answer is A: Labetalol. Labetalol is a non-selective beta blocker with additional alpha-1 blocking properties. This combination of alpha-1 and beta-blocking effects makes it unique among the choices. Alpha-1 blockade helps reduce peripheral vascular resistance, while beta-blocking action decreases heart rate and contractility. This dual mechanism makes labetalol effective in treating hypertension. Betaxolol (B) is a selective beta-1 blocker, Propranolol (C) is a non-selective beta blocker, and Timolol (D) is a non-selective beta blocker as well. These choices lack the alpha-1 blocking effect present in labetalol, making them incorrect for this question.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.