Which of the following drugs has been associated with Reye's syndrome in children?

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

Which of the following drugs has been associated with Reye's syndrome in children?

Correct Answer: A

Rationale: Aspirin (choice A) is linked to Reye's syndrome, a rare liver/brain disorder in children post-viral infection. Acetaminophen (choice B), Ibuprofen (choice C), and Naproxen (choice D) aren't associated. This contraindication limits aspirin's pediatric use.

Question 2 of 5

Which of the following drugs would be most appropriate for the 49-year-old woman complaining of sleep disturbances?

Correct Answer: C

Rationale: Eszopiclone is a nonbenzodiazepine sedative-hypnotic that is commonly used to treat insomnia. It helps patients fall asleep faster and stay asleep longer, making it a suitable option for the woman experiencing sleep disturbances.

Question 3 of 5

Which of the following antihypertensive agents should be avoided in elderly patients?

Correct Answer: B

Rationale: Methyldopa is associated with a high risk of orthostatic hypotension sedation and cognitive impairment in elderly patients.

Question 4 of 5

A 73-year-old man presents to his primary care physician complaining of a weak stream and nocturia four times at night. He is very sensitive to the medication side effects and is reluctant to take medications for this reason. Physical examination reveals a mildly enlarged prostate. Treatment of this condition may involve the use of which of the following agents to minimize side effects?

Correct Answer: D

Rationale: Tamsulosin is an α1-adrenergic receptor antagonist that is selective for the prostate and bladder neck, minimizing systemic side effects like hypotension.

Question 5 of 5

In the treatment of congenital adrenal hyperplasia in which there is excess production of cortisol precursor, the purpose of administration of synthetic glucocorticoid is:

Correct Answer: D

Rationale: In CAH (choice D), synthetic glucocorticoids suppress ACTH, reducing adrenal precursor excess (e.g., 17-hydroxyprogesterone). Aldosterone (choice A), renal (choice B), and immune (choice C) effects aren't primary goals. ACTH suppression corrects the defect.

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