ATI RN
Pharmacology of CNS Drugs Questions
Question 1 of 4
Which of the following drugs can cause lactic acidosis:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 4
Which of the following drugs is taken during the first part of a meal for the purpose of delaying the absorption of dietary carbohydrates?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 4
A 55-year-old woman is noted to be taking tamoxifen to help with breast cancer. She also complains of vaginal bleeding. She asks why she is having vaginal bleeding. Which of the following is the best explanation?
Correct Answer: C
Rationale: Tamoxifen (choice C), a SERM, acts as an estrogen antagonist in breast tissue, inhibiting cancer growth, but as an agonist in the uterus, stimulating endometrial proliferation, which can cause vaginal bleeding due to hyperplasia. Choice A incorrectly suggests agonism in the breast, choice B misstates uterine antagonism, and choice D ignores its uterine effect. This tissue-selective action explains the bleeding, a known side effect requiring monitoring, as it increases endometrial cancer risk. Understanding tamoxifen's dual role is critical for managing breast cancer patients, balancing therapeutic benefits against uterine complications.
Question 4 of 4
Which of the following vitamin D preparations would be the most appropriate in a patient with poor renal function?
Correct Answer: B
Rationale: Calcitriol (choice B), active 1,25-dihydroxyvitamin D, bypasses renal activation, ideal for poor renal function where 1-alpha-hydroxylation is impaired. Calcifediol (choice A), Cholecalciferol (choice C), and Ergocalciferol (choice D) require renal conversion, less effective here. Calcitriol directly corrects hypocalcemia.